Evidence supporting the use of: Omega-3
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Omega-3 fatty acids, particularly docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), have substantial scientific support for their role in eye health. DHA is a major structural component of the retina, and adequate levels are crucial for maintaining retinal function. Clinical trials and epidemiological studies indicate that omega-3s may help reduce the risk or slow the progression of age-related macular degeneration (AMD), one of the leading causes of vision loss in older adults. The Age-Related Eye Disease Study 2 (AREDS2), a large randomized controlled trial, found that while omega-3 supplementation did not further reduce the risk of AMD progression when added to other nutrients, observational studies consistently show an association between higher dietary intake of omega-3s and lower risk of AMD. Additionally, omega-3 supplementation has been shown to reduce symptoms of dry eye disease, improving tear production and ocular surface health in several clinical trials. The mechanism is thought to involve anti-inflammatory effects and improved function of the meibomian glands. Overall, the scientific consensus supports the use of omega-3s for supporting eye health, particularly in the context of dry eye disease and possibly AMD, though the evidence for prevention or treatment of other eye conditions remains less robust.

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