Evidence supporting the use of: Polyphenols (mixed)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polyphenols, a diverse group of phytochemicals found in foods like fruits, vegetables, tea, and cocoa, have been investigated for their potential benefits in supporting eye health. Scientific research suggests that polyphenols possess antioxidant and anti-inflammatory properties, which may be relevant for protecting ocular tissues from oxidative stress and inflammation—two major contributors to eye diseases such as age-related macular degeneration (AMD), cataracts, and diabetic retinopathy.

Several observational and experimental studies have shown that diets rich in polyphenol-containing foods are associated with a reduced risk of developing certain eye conditions. For example, flavonoids (a type of polyphenol) found in berries, tea, and citrus fruits have been linked to improved retinal blood flow and decreased risk of AMD. Laboratory studies suggest that specific polyphenols, such as resveratrol and quercetin, can protect retinal cells from oxidative damage in vitro. However, clinical trials in humans are limited and results are sometimes inconsistent, with some studies showing modest benefits and others showing no significant effect.

Overall, while there is a reasonable scientific rationale and some supportive evidence for the use of polyphenols to promote eye health, the strength of the evidence is moderate rather than robust, and more high-quality clinical studies are needed to clarify their effectiveness and optimal dosing.

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