Evidence supporting the use of: Polyphenols (unspecified)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polyphenols are a diverse group of naturally occurring compounds found in plants, well known for their antioxidant properties. Scientific evidence supports the potential role of polyphenols in supporting eye health, particularly in relation to oxidative stress-related conditions such as age-related macular degeneration (AMD) and cataracts. Research indicates that oxidative damage contributes significantly to the development and progression of these eye diseases. Polyphenols—especially those found in green tea (catechins), grapes (resveratrol), and berries (anthocyanins)—have been shown in laboratory and some clinical studies to protect retinal cells and reduce oxidative stress in ocular tissues.

For example, studies have demonstrated that flavonoids and other polyphenols may help maintain retinal health by scavenging reactive oxygen species and modulating inflammatory pathways. Some epidemiological studies suggest that diets rich in polyphenols are associated with a lower risk of certain eye diseases. However, while animal and in vitro studies are promising, human clinical trials remain limited and results are sometimes inconsistent regarding direct benefits for eye diseases. Thus, while there is scientific validation for the antioxidant and potentially protective effects of polyphenols on eye health, the overall strength of evidence is moderate, justifying a rating of 3 out of 5.

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