Evidence supporting the use of: Proanthocyanidin
For the body system: Eyes
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Proanthocyanidins are a class of polyphenols found in various plants, including grapes, berries, and pine bark. Their use for supporting eye health is primarily based on their antioxidant properties, which may help protect ocular tissues from oxidative stress. Several laboratory and animal studies suggest that proanthocyanidins can protect retinal cells from oxidative damage and may improve microcirculation in the retina, potentially benefiting eye health. Some small clinical studies have evaluated extracts rich in proanthocyanidins, such as grape seed extract or Pycnogenol (French maritime pine bark extract), for their effect on eye health, particularly in conditions like diabetic retinopathy or improving visual function in healthy individuals. However, these studies are generally small, sometimes lack rigorous controls, and results are not always consistent.
Currently, there is insufficient large-scale, high-quality clinical evidence to robustly support the use of proanthocyanidins specifically for eye health in humans. While their antioxidant capabilities are well-established, their direct impact on preventing or treating eye diseases remains under investigation. Therefore, the evidence for supporting the eyes with proanthocyanidins is scientific in nature but limited, warranting a moderate evidence rating.
Other ingredients that support Eyes
acetyl l-carnitinealgal oil
alpha-carotene
anchovies
anthocyanins
apricot
astaxanthin
berry flavor
beta-carotene
bilberry
black currant
blackberry
blueberry
broccoli
calamari oil
carrot
citicoline
cryptoxanthin
d-alpha tocopherol
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
fruit and vegetable blend (proprietary)
gooseberry
hyaluronic acid
hypromellose
kale
l-carnosine
l-taurine
lutein
mackerel
mannitol
marine lipid
melatonin
mixed carotenoids
omega-3 fatty acids
orange
pine bark
pumpkin
riboflavin (vitamin B2)
rutin
saffron
sardines
shrimp
spinach
tomato
triphala
vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
water
mulberry
zeaxanthin
zinc
chickweed
morus
chrysanthemum
haliotis
polyphenols
trace minerals
goji berry
herbal blend (proprietary)
algae
3,3'-dihydroxy-B-carotene-4,4'-dione
Aronia melanocarpa
Alchornea
Avocado
anthocyanidins
anthocyanosides
beta-zeacarotene
Beef liver
Blakeslea trispora
berry
Bioflavonoids
Bee products
Barbary matrimony vine
Crocin
Carnosine
Cod Liver Oil
Cyanidin
Cornflower
Cantaloupe
Chinese Ligustrum berry
Cornus
Carotene (unspecified)
Crocetin
Cocklebur
Crypthecodinium
Celosia
Capsanthin
Currant
Dunaliella salina
Docosahexaenoic Acid
Dunaliella
Egg
Ergothioneine
Eyebright
Eicosapentaenoic Acid
Fruit
Flavonoids
Fish
Fatty acids
Fagopyrum
Flavoglycosides
fibroblast growth factor
Gac
Ginkgo Flavone Glycoside
Glutathione
Gamma-carotene
Rose
Squid
Squash
Other body systems supported by Proanthocyanidin
ArteriesBlood
Capillaries
Circulatory System
Eyes
Gums
Heart
Immune System
Skin
Urinary System
Veins