Evidence supporting the use of: Proanthocyanidins
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Proanthocyanidins, a class of polyphenolic compounds found in foods such as grapes, berries, and cocoa, are known for their potent antioxidant properties. Their use to support eye health is primarily based on their ability to combat oxidative stress, which plays a significant role in the development of age-related eye disorders such as cataracts and macular degeneration. Some scientific studies, including small clinical trials and animal studies, suggest that proanthocyanidins may protect retinal cells and capillaries, contributing to the maintenance of visual function. For example, grape seed extract, which is rich in proanthocyanidins, has demonstrated protective effects against oxidative damage in ocular tissues in preclinical models. However, robust, large-scale human clinical trials directly linking proanthocyanidin supplementation to improved eye health or prevention of eye disease are limited. As such, while there is some scientific rationale and early evidence supporting their use for eye health, the overall quality and quantity of evidence remain moderate at best, justifying a middling rating. More rigorous clinical research is needed to definitively establish efficacy.

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3,3'-dihydroxy-B-carotene-4,4'-dione
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Alchornea
Algae
algal oil
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anchovies
anthocyanidins
anthocyanins
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apricot
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avocado
barbary matrimony vine
bee products
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berry
beta-carotene
beta-zeacarotene
bilberry
bioflavonoids
black currant
blackberry
Blakeslea trispora
blueberry
broccoli
calamari oil
cantaloupe
capsanthin
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carotene (unspecified)
carrot
Celosia
chickweed
Chinese Ligustrum berry
chrysanthemum
citicoline
cocklebur
cod liver oil
cornflower
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crocetin
crocin
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cryptoxanthin
currant
cyanidin
d-alpha tocopherol
DHA (docosahexaenoic acid)
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Dunaliella
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egg
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
ergothioneine
Eyebright
Fagopyrum
fat liver oil
fatty acids
fibroblast growth factor
fish
fish oil
flavoglycosides
flavonoids
flavonols
fruit
fruit and vegetable blend (proprietary)
Gac
gamma-carotene
ginkgo flavone glycoside
Glutathione
goji berry
gooseberry
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haliotis
herbal blend (proprietary)
huckleberry
hyaluronic acid
Idebenone
kale
L-carnosine
L-taurine
Ligustrum
lipids
lutein
Lycium
marigold
Marine fat
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Melatonin
Mineral ascorbate
mixed carotenoids
Morus
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N-Acetyl Carnosine
Oligomeric proanthocyanidins
omega-3 fatty acids
orange
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pine bark
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polyunsaturated fat
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rose
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rutin
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trace minerals
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vitamin A
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Products containing proanthocyanidins

We currently have no products on Vitabase that contain this ingredient.