Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Procyanidol, more commonly known as procyanidolic oligomers (PCOs) or proanthocyanidins, are a class of polyphenolic compounds found in various plants, most notably in grape seeds and pine bark. There is scientific evidence suggesting that these compounds can support eye health, primarily due to their antioxidant properties. Oxidative stress is known to play a role in the development of several eye disorders, including age-related macular degeneration (AMD) and cataracts. Proanthocyanidins have demonstrated the ability to scavenge free radicals and protect ocular tissues from oxidative damage in both in vitro and animal studies.

Several small human trials and observational studies have explored the effects of proanthocyanidin-rich extracts (such as from grape seed or French maritime pine bark, i.e., Pycnogenol®) on eye health. Some studies report improvements in retinal microcirculation, reduction in visual stress, and potential benefits for diabetic retinopathy, likely through their effects on capillary permeability and vascular health. However, while the results are promising, most clinical studies are relatively small, short-term, or have methodological limitations. Systematic reviews acknowledge the antioxidant and vascular benefits of proanthocyanidins but call for larger, high-quality trials to confirm efficacy for specific eye conditions.

In summary, there is scientific rationale and some supportive data for the use of procyanidol (proanthocyanidins) in supporting the eye body system, but the strength of evidence is moderate rather than robust.

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3,3'-dihydroxy-B-carotene-4,4'-dione
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Alchornea
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algal oil
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anchovies
anthocyanidins
anthocyanins
anthocyanosides
apricot
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avocado
barbary matrimony vine
bee products
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berry
beta-carotene
beta-zeacarotene
bilberry
bioflavonoids
black currant
blackberry
Blakeslea trispora
blueberry
broccoli
calamari oil
cantaloupe
capsanthin
Carnosine
carotene (unspecified)
carrot
Celosia
chickweed
Chinese Ligustrum berry
chrysanthemum
citicoline
cocklebur
cod liver oil
cornflower
Cornus
crocetin
crocin
Crypthecodinium
cryptoxanthin
currant
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d-alpha tocopherol
DHA (docosahexaenoic acid)
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Dunaliella
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egg
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
ergothioneine
Eyebright
Fagopyrum
fat liver oil
fatty acids
fibroblast growth factor
fish
fish oil
flavoglycosides
flavonoids
flavonols
fruit
fruit and vegetable blend (proprietary)
Gac
gamma-carotene
ginkgo flavone glycoside
Glutathione
goji berry
gooseberry
Haematococcus pluvialis
haliotis
herbal blend (proprietary)
huckleberry
hyaluronic acid
Idebenone
kale
L-carnosine
L-taurine
Ligustrum
lipids
lutein
Lycium
marigold
Marine fat
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Melatonin
Mineral ascorbate
mixed carotenoids
Morus
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N-Acetyl Carnosine
Oligomeric proanthocyanidins
omega-3 fatty acids
orange
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polyunsaturated fat
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riboflavin (vitamin B2)
rose
rue
rutin
saffron
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Schizochytrium
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spinach
Tagetes
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trace minerals
Triphala
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vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
Xanthophyll
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Other body systems supported by procyanidol

Arteries
Capillaries
Circulatory System
Eyes
Gums
Veins

Products containing procyanidol

We currently have no products on Vitabase that contain this ingredient.