Evidence supporting the use of: Procyanidol
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Procyanidol, more commonly known as procyanidolic oligomers (PCOs) or proanthocyanidins, are a class of polyphenolic compounds found in various plants, most notably in grape seeds and pine bark. There is scientific evidence suggesting that these compounds can support eye health, primarily due to their antioxidant properties. Oxidative stress is known to play a role in the development of several eye disorders, including age-related macular degeneration (AMD) and cataracts. Proanthocyanidins have demonstrated the ability to scavenge free radicals and protect ocular tissues from oxidative damage in both in vitro and animal studies.

Several small human trials and observational studies have explored the effects of proanthocyanidin-rich extracts (such as from grape seed or French maritime pine bark, i.e., Pycnogenol®) on eye health. Some studies report improvements in retinal microcirculation, reduction in visual stress, and potential benefits for diabetic retinopathy, likely through their effects on capillary permeability and vascular health. However, while the results are promising, most clinical studies are relatively small, short-term, or have methodological limitations. Systematic reviews acknowledge the antioxidant and vascular benefits of proanthocyanidins but call for larger, high-quality trials to confirm efficacy for specific eye conditions.

In summary, there is scientific rationale and some supportive data for the use of procyanidol (proanthocyanidins) in supporting the eye body system, but the strength of evidence is moderate rather than robust.

More about procyanidol
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Other ingredients that support Eyes

Acetyl L-carnitine
algal oil
Alpha-carotene
anchovies
anthocyanins
apricot
astaxanthin
berry flavor
beta-carotene
bilberry
black currant
blackberry
blueberry
broccoli
calamari oil
carrot
citicoline
cryptoxanthin
d-alpha tocopherol
DHA (docosahexaenoic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
fruit and vegetable blend (proprietary)
gooseberry
hyaluronic acid
hypromellose
kale
L-carnosine
L-taurine
lutein
mannitol
Marine lipid
Melatonin
mixed carotenoids
omega-3 fatty acids
orange
pine bark
pumpkin
riboflavin (vitamin B2)
rutin
saffron
spinach
Triphala
vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
Water
Mulberry
Zeaxanthin
Zinc
chickweed
Morus
chrysanthemum
haliotis
polyphenols
trace minerals
goji berry
herbal blend (proprietary)
Algae
3,3'-dihydroxy-B-carotene-4,4'-dione
Aronia melanocarpa
Alchornea
avocado
anthocyanidins
anthocyanosides
beta-zeacarotene
Beef liver
Blakeslea trispora
berry
bioflavonoids
bee products
barbary matrimony vine
crocin
Carnosine
cod liver oil
cyanidin
cornflower
cantaloupe
Chinese Ligustrum berry
Cornus
carotene (unspecified)
crocetin
cocklebur
Crypthecodinium
Celosia
capsanthin
currant
Dunaliella salina
docosahexaenoic Acid
Dunaliella
egg
ergothioneine
Eyebright
eicosapentaenoic acid
fruit
flavonoids
fat liver oil
fish
fatty acids
Fagopyrum
flavoglycosides
fibroblast growth factor
Gac
ginkgo flavone glycoside
Glutathione
gamma-carotene
Haematococcus pluvialis
huckleberry
Idebenone
Lycium
Ligustrum
lipids
Mineral ascorbate
Marine fat
marigold
N-Acetyl Carnosine
Oligomeric proanthocyanidins
Phaffia rhodozyma
procyanidol
proanthocyanidins
polyunsaturated fat
Pycnogenol
Polygonum
rue
rose
Schizochytrium Oil
Spanish Needle
Schizochytrium
Salmon Oil
Tea
Troxerutin
Taurine
Tagetes
Xanthophyll

Other body systems supported by procyanidol

Arteries
Capillaries
Circulatory System
Eyes
Gums
Veins

Products containing procyanidol

We currently have no products on Vitabase that contain this ingredient.