Evidence supporting the use of: Procyanidol
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Procyanidol, more commonly known as procyanidolic oligomers (PCOs) or proanthocyanidins, are a class of polyphenolic compounds found in various plants, most notably in grape seeds and pine bark. There is scientific evidence suggesting that these compounds can support eye health, primarily due to their antioxidant properties. Oxidative stress is known to play a role in the development of several eye disorders, including age-related macular degeneration (AMD) and cataracts. Proanthocyanidins have demonstrated the ability to scavenge free radicals and protect ocular tissues from oxidative damage in both in vitro and animal studies.

Several small human trials and observational studies have explored the effects of proanthocyanidin-rich extracts (such as from grape seed or French maritime pine bark, i.e., Pycnogenol®) on eye health. Some studies report improvements in retinal microcirculation, reduction in visual stress, and potential benefits for diabetic retinopathy, likely through their effects on capillary permeability and vascular health. However, while the results are promising, most clinical studies are relatively small, short-term, or have methodological limitations. Systematic reviews acknowledge the antioxidant and vascular benefits of proanthocyanidins but call for larger, high-quality trials to confirm efficacy for specific eye conditions.

In summary, there is scientific rationale and some supportive data for the use of procyanidol (proanthocyanidins) in supporting the eye body system, but the strength of evidence is moderate rather than robust.

More about Procyanidol
More about Eyes

Other body systems supported by Procyanidol

Arteries
Capillaries
Circulatory System
Eyes
Gums
Veins

Products containing Procyanidol

We currently have no products on Vitabase that contain this ingredient.