Evidence supporting the use of: Riboflavin
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Riboflavin (vitamin B2) is scientifically recognized as an essential nutrient for overall health, including the maintenance of normal vision. It serves as a precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are critical in cellular energy production and antioxidant protection. Deficiency in riboflavin is known to cause ocular symptoms such as photophobia, excessive tearing, and, in severe cases, the development of cataracts. Epidemiological and clinical studies have shown that low riboflavin status is associated with increased risk of certain eye disorders, particularly cataracts. For example, a 2005 meta-analysis published in the International Journal of Vitamin and Nutrition Research found an inverse association between riboflavin intake and risk of age-related cataracts. Additionally, riboflavin is used as part of a medical procedure called corneal cross-linking for keratoconus, where it enhances the strengthening of corneal tissue when activated by UV light. However, while riboflavin’s role in preventing deficiency-related eye problems is well-established, evidence supporting its use as a supplement for improving vision or preventing common eye diseases in well-nourished individuals is limited. Thus, the scientific support is moderate, based mainly on its role in deficiency prevention and specific clinical uses, rather than as a general eye health supplement.

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Products containing Riboflavin

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