Evidence supporting the use of: Rutin
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rutin is a bioflavonoid found in various plants, known for its antioxidant and vasoprotective properties. Its use in supporting eye health is primarily based on its ability to strengthen capillaries and reduce oxidative stress, both of which are relevant to eye health, particularly in conditions like diabetic retinopathy and other microvascular disorders. Several laboratory and animal studies indicate that rutin can help protect retinal cells from oxidative damage and may support vascular integrity in the eye. For example, some research shows that rutin supplementation reduces retinal oxidative stress and protects against experimentally induced retinal injury in animal models.

However, clinical evidence in humans is limited. While small studies and historical use suggest potential benefits in reducing capillary fragility and microbleeds, robust randomized controlled trials specifically examining rutin for eye health or diseases such as macular degeneration or diabetic retinopathy are lacking. Its inclusion in some eye health supplements is often based on extrapolation from its general vascular and antioxidant benefits rather than direct, high-quality clinical evidence for ocular outcomes. In summary, the scientific rationale exists, but the strength of evidence in humans remains modest, warranting a rating of 2 out of 5.

More about rutin
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Other ingredients that support Eyes

Acetyl L-carnitine
algal oil
Alpha-carotene
anchovies
anthocyanins
apricot
astaxanthin
berry flavor
beta-carotene
bilberry
black currant
blackberry
blueberry
broccoli
calamari oil
carrot
citicoline
cryptoxanthin
d-alpha tocopherol
DHA (docosahexaenoic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
fruit and vegetable blend (proprietary)
gooseberry
hyaluronic acid
hypromellose
kale
L-carnosine
L-taurine
lutein
mannitol
Marine lipid
Melatonin
mixed carotenoids
omega-3 fatty acids
orange
pine bark
pumpkin
riboflavin (vitamin B2)
rutin
saffron
spinach
Triphala
vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
Water
Mulberry
Zeaxanthin
Zinc
chickweed
Morus
chrysanthemum
haliotis
polyphenols
trace minerals
goji berry
herbal blend (proprietary)
Algae
3,3'-dihydroxy-B-carotene-4,4'-dione
Aronia melanocarpa
Alchornea
avocado
anthocyanidins
anthocyanosides
beta-zeacarotene
Beef liver
Blakeslea trispora
berry
bioflavonoids
bee products
barbary matrimony vine
crocin
Carnosine
cod liver oil
cyanidin
cornflower
cantaloupe
Chinese Ligustrum berry
Cornus
carotene (unspecified)
crocetin
cocklebur
Crypthecodinium
Celosia
capsanthin
currant
Dunaliella salina
docosahexaenoic Acid
Dunaliella
egg
ergothioneine
Eyebright
eicosapentaenoic acid
fruit
flavonoids
fat liver oil
fish
fatty acids
Fagopyrum
flavoglycosides
fibroblast growth factor
Gac
ginkgo flavone glycoside
Glutathione
gamma-carotene
Haematococcus pluvialis
huckleberry
Idebenone
Lycium
Ligustrum
lipids
Mineral ascorbate
Marine fat
marigold
N-Acetyl Carnosine
Oligomeric proanthocyanidins
Phaffia rhodozyma
procyanidol
proanthocyanidins
polyunsaturated fat
Pycnogenol
Polygonum
rue
rose
Schizochytrium Oil
Spanish Needle
Schizochytrium
Salmon Oil
Tea
Troxerutin
Taurine
Tagetes
Xanthophyll

Other body systems supported by rutin

Arteries
Blood
Capillaries
Circulatory System
Eyes
Heart
Veins