Evidence supporting the use of: Saffron
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Saffron (Crocus sativus) has a longstanding history in traditional medicine for supporting eye health, but in recent years, scientific research has provided validation for its beneficial effects on the visual system. Several clinical studies have indicated that saffron supplementation can have positive effects on certain eye conditions, notably age-related macular degeneration (AMD). Randomized controlled trials have shown that daily doses of saffron (typically 20 mg) can improve visual function in patients with early AMD, likely due to its antioxidant, anti-inflammatory, and neuroprotective properties. The key bioactive compounds in saffron, crocin and crocetin, are believed to protect retinal cells from oxidative stress and improve retinal blood flow. A 2010 study published in the journal Investigative Ophthalmology & Visual Science and subsequent trials have reported statistically significant improvements in retinal function and visual acuity among AMD patients taking saffron. While more extensive research is needed to confirm long-term efficacy and safety, current evidence supports the use of saffron as an adjunct for maintaining eye health, particularly in the context of degenerative retinal diseases. Thus, saffron's role in supporting the eyes is backed by both historical use and a growing body of scientific research.

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