Salmon oil is rich in omega-3 polyunsaturated fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Scientific studies have investigated the role of omega-3 fatty acids in supporting eye health, especially in relation to conditions like dry eye syndrome and age-related macular degeneration (AMD).

Clinical trials and epidemiological research suggest that higher dietary intake of omega-3s is associated with a reduced risk of AMD progression. For example, the Age-Related Eye Disease Study 2 (AREDS2) included omega-3 supplementation, though it found no significant benefit for AMD progression when added to the standard AREDS formulation. However, observational studies have supported a protective association.

For dry eye, some randomized controlled trials have demonstrated improvement in symptoms and tear production with omega-3 supplementation, including from fish oil sources like salmon oil. The anti-inflammatory effects of EPA and DHA are thought to benefit the ocular surface. However, not all clinical trials have shown significant benefit, and systematic reviews report only modest effects.

In summary, there is moderate scientific evidence supporting the use of salmon oil (or omega-3 supplements) for certain eye health concerns, particularly dry eye symptoms and possibly as part of a broader strategy to reduce AMD risk. The evidence base is not unequivocal, but it is sufficient to justify its use for eye health support in some contexts.