Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Superoxide Dismutase (SOD) is an antioxidant enzyme that catalyzes the dismutation of superoxide radicals into oxygen and hydrogen peroxide, thereby protecting cells from oxidative damage. The eye is particularly susceptible to oxidative stress due to constant exposure to light and high metabolic activity, which has led researchers to investigate antioxidants like SOD in ocular health. Animal studies and some limited human data suggest that SOD levels are important in protecting retinal cells and the lens from oxidative injury, which is implicated in conditions such as age-related macular degeneration (AMD) and cataract formation. For example, decreased SOD activity has been observed in the lenses of patients with cataracts, and experimental models show that enhancing SOD activity can reduce damage from oxidative stress in ocular tissues. However, the evidence that oral or topical SOD supplementation directly improves eye health in humans is limited and mixed. Issues such as SOD's bioavailability and delivery to ocular tissues remain challenges. Consequently, while there is scientific rationale and some preclinical evidence supporting a protective role for SOD in eye health, robust clinical trials demonstrating efficacy of SOD supplementation for eye conditions are lacking. Therefore, the scientific support for using SOD to support the eye body system is modest and not yet definitive.

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Other body systems supported by Superoxide Dismutase

Arteries
Blood
Brain
Circulatory System
Eyes
Gastrointestinal Tract
Heart
Immune System
Intestinal System
Liver
Lungs
Mitochondria
Muscles
Skin

Products containing Superoxide Dismutase

We currently have no products on Vitabase that contain this ingredient.