Evidence supporting the use of: Troxerutin
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Troxerutin is a flavonoid derived from rutin and is used primarily for its vasoprotective properties. Scientific evidence supports its use for the eyes, particularly in the context of diabetic retinopathy and other microvascular complications affecting ocular health. Multiple animal studies and some human clinical trials have shown that troxerutin can reduce capillary permeability, strengthen blood vessel walls, and improve microcirculation. These effects are beneficial in conditions like diabetic retinopathy, where microvascular damage plays a key role in disease progression. In several studies, troxerutin demonstrated antioxidant and anti-inflammatory properties, which help to protect retinal cells from oxidative stress—a contributing factor in many eye diseases. However, while the evidence is promising, most clinical studies are small or preliminary, and more large-scale, rigorous trials are needed to confirm its efficacy and safety for ocular support. The European Medicines Agency and other authoritative bodies recognize troxerutin’s role in vascular health, but its application specifically for eye health is not yet universally endorsed. Thus, troxerutin’s support for the eye system is backed by moderate scientific evidence, particularly in the context of vascular-related eye conditions.

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