Evidence supporting the use of: Vitamin A (not specified)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin A is scientifically validated as essential for supporting the eyes and vision. The most critical role of vitamin A in eye health is its function as a component of rhodopsin, a protein in the retina that absorbs light and is necessary for low-light (scotopic) vision. Deficiency of vitamin A is well established as a leading cause of preventable blindness, particularly in children in developing countries. Clinical manifestations of deficiency include night blindness, xerophthalmia (dryness of the conjunctiva and cornea), and, in severe cases, complete blindness due to corneal ulceration and necrosis. Numerous clinical studies and public health interventions have shown that vitamin A supplementation reduces the risk of blindness and improves visual function in populations at risk of deficiency. In addition, vitamin A supports the maintenance of healthy conjunctival membranes and corneal surfaces. The scientific evidence supporting the connection between vitamin A and eye health is robust, and its use is endorsed by major health organizations such as the World Health Organization (WHO) and the American Academy of Ophthalmology. However, excessive intake of vitamin A can be toxic and may cause adverse health outcomes, so supplementation should be approached with caution, particularly in populations not at risk for deficiency.

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