Evidence supporting the use of: Vitamin A (retinol)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin A (retinol) is strongly supported by scientific evidence for its essential role in maintaining eye health. Vitamin A is a critical component of the visual cycle; it is a precursor to the retinal molecule that forms rhodopsin, a pigment in the eye’s retina that is necessary for both low-light (scotopic) and color vision. Deficiency in vitamin A is a well-established cause of night blindness and, in severe cases, can lead to xerophthalmia and irreversible blindness. The World Health Organization (WHO) recognizes vitamin A deficiency as a leading cause of preventable childhood blindness globally. Numerous clinical studies and decades of nutritional research have demonstrated that vitamin A supplementation prevents and treats deficiency-related ocular disorders, especially in at-risk populations. In addition, vitamin A plays a supporting role in maintaining the structural integrity of conjunctival membranes and corneal tissues. The use of vitamin A in this context is not based on tradition alone, but rather on robust, mechanistic, and clinical data. Therefore, the use of retinol to support eye health is scientifically validated and forms the basis for public health interventions in many countries.

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