Evidence supporting the use of: Vitamin B2 (Riboflavin)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B2 (Riboflavin) is scientifically recognized as essential for maintaining normal vision and supporting eye health, primarily due to its role in cellular metabolism and protection against oxidative stress. Riboflavin is a precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), both of which are crucial for energy production and antioxidant functions in ocular tissues. Riboflavin deficiency has been associated with ocular symptoms such as photophobia, itching, burning, and bloodshot eyes, as well as the development of cataracts. Some research, including observational studies, has found that adequate riboflavin intake may be associated with a reduced risk of cataract formation. For example, a study published in the American Journal of Clinical Nutrition (1999) found that lower riboflavin intake was linked to a higher risk of age-related cataracts in certain populations. However, clinical intervention trials demonstrating that riboflavin supplementation prevents or treats eye disease are limited and the effects appear modest. Overall, vitamin B2 is justified for eye health based on its essential physiological functions and observational evidence linking deficiency to ocular issues, but direct therapeutic benefits in eye disease prevention or treatment require further research.

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