Evidence supporting the use of: Vitamin B2 (riboflavin 5-phosphate)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B2, also known as riboflavin or riboflavin 5-phosphate (its active coenzyme form), has scientific support for its role in eye health. Riboflavin is essential for maintaining normal vision because it functions as a cofactor in redox reactions that protect ocular tissues from oxidative stress. Deficiency in riboflavin can lead to ocular symptoms such as photophobia, excessive tearing, and even cataract formation. Multiple studies have shown that adequate riboflavin intake is associated with a lower risk of developing cataracts, a common age-related eye condition. For instance, epidemiological studies indicate that populations with higher riboflavin intake or status have a reduced incidence of certain types of cataracts (Arch Ophthalmol. 2000; Am J Clin Nutr. 1993). Additionally, riboflavin is used in a medical procedure called corneal collagen cross-linking, where it acts as a photosensitizer to strengthen corneal tissue in people with keratoconus. While supplementation beyond recommended daily allowance is not universally shown to further reduce risk of eye diseases in all individuals, the essential role of riboflavin in ocular metabolism and its deficiency syndromes are well-documented. Therefore, riboflavin’s use to support eye health is justified by scientific evidence, particularly for preventing deficiency-related problems and as a cofactor in eye tissue protection.

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Other body systems supported by Vitamin B2 (riboflavin 5-phosphate)

Blood
Brain
Digestive System
Eyes
Hepatic System
Immune System
Intestinal System
Liver
Mitochondria
Nerves
Skin

Products containing Vitamin B2 (riboflavin 5-phosphate)

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