Evidence supporting the use of: Vitamin B2 (Riboflavin Phosphate)
For the body system: Eyes

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B2, also known as riboflavin (and as riboflavin phosphate in certain supplements), has a scientifically supported role in maintaining normal eye health. Riboflavin is an essential component of the cofactors FAD and FMN, which play a crucial part in cellular energy production and antioxidant protection. The lens of the eye is especially susceptible to oxidative damage, and riboflavin helps by supporting glutathione regeneration, a key antioxidant in the lens. Deficiency in riboflavin has been linked in both animal and human studies to the development of cataracts—a clouding of the lens that impairs vision. Some observational studies and limited clinical trials suggest that adequate riboflavin intake may reduce cataract risk or delay its progression, though the evidence is not robust enough for universal recommendations beyond addressing deficiency. The use of riboflavin eye drops has also been studied as a photosensitizer in corneal cross-linking procedures for keratoconus, but this is a medical intervention rather than a nutritional effect. Overall, while there is scientific basis for riboflavin’s importance in general eye health and in the prevention of deficiency-related eye disorders, its supplementation above recommended daily intake for eye health is not strongly supported by high-quality interventional trials.

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Other body systems supported by Vitamin B2 (Riboflavin Phosphate)

Blood
Brain
Digestive System
Eyes
Glandular System
Immune System
Mitochondria
Nerves
Skin

Products containing Vitamin B2 (Riboflavin Phosphate)

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