Evidence supporting the use of: Vitamin B2 (riboflavin selenite)
For the body system: Eyes
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Vitamin B2, known as riboflavin (not "riboflavin selenite," as riboflavin is not typically bound to selenium in supplements), plays a well-established role in supporting eye health. Riboflavin is an essential component of two major coenzymes: flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are crucial for energy production and cellular function. The eyes have a high metabolic rate and require significant energy, making riboflavin particularly important for ocular tissue metabolism.
Scientific studies have demonstrated that riboflavin deficiency can lead to eye-related symptoms such as photophobia, excessive tearing, itching, and eventually cataract formation. Riboflavin has antioxidant properties that help protect the lens and other ocular tissues from oxidative stress, a key factor in the development of cataracts. Epidemiological studies have shown that adequate dietary intake of riboflavin is associated with a reduced risk of age-related cataracts. Furthermore, riboflavin is used therapeutically in combination with ultraviolet A (UVA) light for corneal cross-linking, a procedure that strengthens the cornea in patients with keratoconus.
While supplementation beyond the recommended daily allowance does not appear to provide additional benefits for healthy individuals, riboflavin’s role in maintaining eye health is well supported by biochemical, clinical, and epidemiological evidence. Therefore, its use to support the eyes body system is scientifically validated.
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