Evidence supporting the use of: Vitamin B2 (unspecified)
For the body system: Eyes

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B2, also known as riboflavin, has scientific backing for its role in maintaining eye health. Riboflavin is a water-soluble vitamin that acts as a precursor for the cofactors FMN (flavin mononucleotide) and FAD (flavin adenine dinucleotide), both of which are critical for cellular energy production and antioxidant defense mechanisms. In the context of ocular health, riboflavin deficiency has been associated with symptoms such as photophobia, excessive tearing, eye fatigue, and, in severe cases, the development of cataracts. Several epidemiological studies suggest a correlation between adequate riboflavin intake and a reduced risk of cataract formation, likely due to riboflavin's antioxidant properties that help protect the lens from oxidative damage. Furthermore, riboflavin is utilized therapeutically in corneal collagen cross-linking procedures for keratoconus, where riboflavin eye drops combined with UV light help strengthen corneal tissue. However, while there is a reasonable body of clinical and preclinical evidence supporting riboflavin's importance for eye health and its role in preventing certain eye disorders, large-scale randomized controlled trials are limited. Thus, the evidence is considered moderate (3 out of 5) but clearly points to a valid scientific rationale for riboflavin's use in supporting the eyes.

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