Evidence supporting the use of: Vitamin C (mixed ascorbates)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin C, including in the form of mixed ascorbates, is used to support eye health based on scientific evidence, particularly regarding its role in reducing the risk of age-related eye diseases. Vitamin C is a potent antioxidant, helping to neutralize free radicals and reduce oxidative stress, which is implicated in the development of cataracts and age-related macular degeneration (AMD).

Several observational and interventional studies have examined Vitamin C’s role in eye health. The Age-Related Eye Disease Study (AREDS), a large, multi-center clinical trial, found that a combination of antioxidants (including Vitamin C, Vitamin E, and beta-carotene) plus zinc reduced the risk of progression to advanced AMD in high-risk individuals. While Vitamin C alone was not isolated as the sole effective compound, it is a key component of the antioxidant defense system in the eye.

Additionally, some epidemiological research suggests that individuals with higher dietary intake of Vitamin C have a lower risk of developing cataracts. However, evidence from randomized controlled trials is mixed regarding supplementation's ability to prevent or slow cataract progression.

In summary, there is scientific support for Vitamin C as part of an antioxidant strategy to support eye health, particularly in reducing the risk of certain age-related conditions. However, the evidence is stronger for its use as part of a combination therapy rather than as a single agent.

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