Evidence supporting the use of: Vitamin E (mixed)
For the body system: Eyes

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E, a group of fat-soluble antioxidants, has been studied for its potential role in supporting eye health, particularly regarding age-related macular degeneration (AMD) and cataracts. The most notable clinical evidence comes from the Age-Related Eye Disease Study (AREDS and AREDS2), in which a high-dose antioxidant formula—including vitamin E, vitamin C, beta-carotene (later replaced with lutein/zeaxanthin), zinc, and copper—was shown to slow the progression of intermediate to advanced AMD. However, vitamin E alone has not been demonstrated to provide significant benefit for eye health or to prevent AMD or cataracts in large, well-controlled studies. Meta-analyses and review articles typically find that while oxidative stress is implicated in ocular diseases, supplementation with vitamin E by itself does not consistently reduce the risk or progression of these conditions. Most professional guidelines do not recommend vitamin E alone for eye health, but acknowledge its role as part of comprehensive antioxidant regimens. Therefore, while there is some scientific basis for the use of vitamin E in combination therapies for certain eye conditions, the evidence for vitamin E as a stand-alone supplement to support the eyes is limited and not robust.

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