Evidence supporting the use of: Vitamin E (not specified)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E is an antioxidant that has been investigated for its potential role in supporting eye health, particularly in relation to age-related macular degeneration (AMD) and cataract prevention. Several large epidemiological studies, such as the Age-Related Eye Disease Study (AREDS), have evaluated Vitamin E (in combination with other antioxidants and zinc) for reducing the progression of AMD. The AREDS and AREDS2 trials found that while the combination of antioxidants (vitamin C, vitamin E, beta-carotene, zinc, and copper) modestly reduced the risk of progression to advanced AMD in high-risk individuals, vitamin E alone did not show a significant benefit when isolated from the combination. Other randomized controlled trials and meta-analyses have largely failed to demonstrate a consistent or significant protective effect of vitamin E supplementation alone on cataract formation or overall eye health in the general population.

Despite its widespread use and theoretical antioxidant benefit, current scientific evidence does not strongly support Vitamin E supplementation by itself for maintaining or improving eye health in the absence of deficiency. However, it remains part of some antioxidant formulations used in specific, high-risk populations for slowing the progression of AMD. As such, the evidence for Vitamin E supporting eye health is limited and best characterized as modest when used in combination with other nutrients rather than as a standalone intervention.

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