Evidence supporting the use of: Vitamin E (unspecified)
For the body system: Eyes

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E is an antioxidant that has been investigated for its role in supporting eye health, particularly in relation to age-related macular degeneration (AMD) and cataracts. Several large randomized controlled trials, such as the Age-Related Eye Disease Study (AREDS and AREDS2), included Vitamin E as part of a combination antioxidant formula. These studies found that the combination could slow the progression of intermediate to advanced AMD, but Vitamin E alone was not shown to be effective. Some observational studies have linked higher dietary intake of Vitamin E with a reduced risk of cataracts or AMD, but interventional studies using Vitamin E supplementation alone have not demonstrated clear, consistent benefit for eye health.

Overall, while the antioxidant properties of Vitamin E provide a theoretical rationale for its use in protecting ocular tissues from oxidative stress, scientific validation for its use as a standalone supplement for eye health is limited. The evidence supports its use only as part of a broader antioxidant regimen, rather than as a single agent. Thus, the strength of evidence supporting Vitamin E alone for eye health is modest (rated 2/5), and supplementation is not generally recommended solely for eye support without specific clinical indications.

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