Evidence supporting the use of: Xanthophyll
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Xanthophylls, particularly lutein and zeaxanthin, are carotenoid pigments found in high concentrations in the macula of the human retina. Their use for eye health is primarily supported by scientific research. Numerous epidemiological and interventional studies have demonstrated that higher dietary intake and supplementation of lutein and zeaxanthin are associated with a reduced risk of age-related macular degeneration (AMD) and cataracts. These xanthophylls act as antioxidants, neutralizing free radicals, and as blue-light filters, protecting retinal tissues from phototoxic damage.

The Age-Related Eye Disease Study 2 (AREDS2), a large, multi-center randomized trial sponsored by the National Eye Institute, found that supplementation with lutein and zeaxanthin could further reduce the risk of progression to advanced AMD, especially in individuals with low dietary intake of these carotenoids. Other clinical trials and meta-analyses have corroborated these findings, showing modest but statistically significant improvements in macular pigment optical density and visual performance among supplement users.

While not all studies show strong effects, the overall body of evidence supports the use of xanthophylls for maintaining eye health and reducing the risk of certain degenerative eye conditions. Therefore, their use in eye health supplements has a robust scientific basis.

More about Xanthophyll
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Other body systems supported by Xanthophyll

Eyes
Skin

Products containing Xanthophyll

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