Evidence supporting the use of: Omega-3 fatty acids
For the health condition: Eyes (red or itching)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been scientifically investigated for their role in supporting eye health, especially in conditions associated with redness, itching, and dryness—symptoms commonly seen in dry eye disease. Several randomized controlled trials and meta-analyses have indicated that omega-3 supplementation can reduce symptoms of dry eye, which often include redness and itching. The mechanism appears to involve anti-inflammatory effects: omega-3 fatty acids help modulate the production of inflammatory mediators, leading to reduced ocular surface inflammation and improved tear film stability.
For example, a 2016 meta-analysis in the journal Cornea concluded that omega-3 supplementation significantly improved tear break-up time and reduced dry eye symptoms compared to placebo. The DREAM study (2018), a large, well-designed trial, found no statistically significant benefit over placebo, though the placebo response was unusually strong in this study. Despite mixed results, many ophthalmologists recommend omega-3s as a safe adjunct for managing dry eye symptoms, including redness and itching.
While omega-3s are not typically used for acute allergic conjunctivitis or severe infections, there is sufficient scientific evidence to justify their use as part of a long-term strategy for managing chronic dry eye syndrome and associated symptoms. However, the overall strength of the evidence is moderate, reflecting some inconsistencies in clinical outcomes and the need for further research.
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goldenseal
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schizonepeta
vitamin A
zinc
chickweed
neem tree
chrysanthemum
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anthocyanosides
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Other health conditions supported by omega-3 fatty acids
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Eyes (red or itching)
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Hair Care (general)
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Advanced DHA
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Douglas Laboratories
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Krill-Plex
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Metagenics
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Metagenics
OmegaGenics EPA-DHA 300 Lemon Lime
Metagenics
OmegaGenics Fish Oil EPA-DHA 1000 mg
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OmegaGenics Fish Oil EPA-DHA 1000 mg
Metagenics
OmegaGenics Fish Oil EPA-DHA 500 mg
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OmegaGenics Fish Oil EPA-DHA 720 mg
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OmegaGenics Fish Oil EPA-DHA 720 mg
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OmegaGenics Fish Oil EPA-DHA 720 mg
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OmegaGenics Fish Oil Mega 10®
Designs For Health
OmegAvail™ Synergy
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OmegAvail™ TG1000
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OmegAvail™ Ultra
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OmegAvail™ Ultra
Designs For Health
OmegAvail™ Ultra DHA
Designs For Health
OmegAvail™ Ultra with Vitamin D3, K1 and K2
Thorne
Prenatal DHA
Pure Encapsulations
Pro-Resolve Omega
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Pro-Resolving Mediators
Integrative Therapeutics
Pure Omega HP
Integrative Therapeutics
Pure Omega Liquid
Integrative Therapeutics
Pure Omega Ultra HP
Pure Encapsulations
PureNutrients EPA/DHA
Douglas Laboratories
QÜELL® FISH OIL DHA Ultra SPM
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QUELL Fish Oil ® - EPA/DHA Plus D
Thorne
Super EPA
Pure Encapsulations
VisionPro EPA/DHA/GLA
Pure Encapsulations
VisionPro EPA/DHA/GLA