Evidence supporting the use of: Anthocyanosides
For the health condition: Eyesight (poor)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanosides, a group of flavonoid pigments found in various fruits like bilberries and blackcurrants, have been traditionally used for eye health, but there is also some scientific investigation into their effects on vision. Research, primarily centered on bilberry extract (rich in anthocyanosides), suggests possible benefits for improving night vision and reducing eye fatigue. Some small clinical studies, particularly during and after World War II, reported improved night vision in pilots consuming bilberry. More recent studies have explored anthocyanosides' antioxidant properties, theorizing that they may protect retinal cells from oxidative stress, which is implicated in age-related eye conditions. However, systematic reviews and larger, well-controlled trials have generally found the evidence to be inconclusive or weak, with many studies suffering from methodological issues, small sample sizes, and inconsistent results. The American Academy of Ophthalmology and similar organizations state that there is insufficient clinical evidence to recommend anthocyanosides for treating poor eyesight or preventing age-related eye diseases. Thus, while there is some scientific investigation and theoretical rationale, robust clinical validation is lacking, and anthocyanosides should not be considered a proven therapy for poor eyesight.

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