Evidence supporting the use of: Bile salt
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Bile salts are used to support fat metabolism, particularly in individuals with poor fat digestion due to biliary insufficiency or related conditions. Scientifically, bile salts play a crucial role in the emulsification and absorption of dietary fats and fat-soluble vitamins (A, D, E, K) in the small intestine. In cases where the body's own bile production or secretion is inadequate—such as after gallbladder removal (cholecystectomy), chronic liver disease, or specific genetic disorders—supplementing with bile salts (such as ox bile extract) can help restore fat digestion and absorption.
Clinical evidence supports the use of bile salts for individuals with documented bile acid deficiency. Several studies have shown that bile salt supplementation can improve symptoms like steatorrhea (fatty stools), bloating, and fat-soluble vitamin deficiencies in such patients. However, the evidence is less robust for the use of bile salts in the general population or for vague symptoms of "poor fat metabolism" without a clear underlying cause. The majority of clinical trials and case studies are focused on populations with specific medical diagnoses rather than healthy individuals or those with minor complaints.
In summary, the use of bile salts to support fat metabolism is scientifically justified in specific clinical contexts involving bile deficiency. There is moderate-quality evidence (rating 3/5) supporting their use for these medical indications, but not for general wellness or unproven "fat metabolism" issues.
Other ingredients used for Fat Metabolism (poor)
7-Keto-DHEAAcetyl L-carnitine
alpha-linolenic acid (ALA)
anchovies
artichoke
barberry
biotin
canola oil
capsaicinoids
choline
cinnamon
Coleus forskohlii
conjugated linoleic acid (CLA)
turmeric
dandelion
epigallocatechin gallate (EGCG)
fenugreek
flavonols
forskohlii root
garcinia
ginger
glucomannan
guggul
hesperetin
hydroxycitric acid
kelp
l-carnitine
lecithin
linoleic acid (LA)
lipase
medium chain triglycerides (MCT)
Milk thistle
omega-3 fatty acids
omega-7 fatty acids
palmitate
pantethine
phospholipids
black ginger
vitamin B
Zinc
bile salt
polyphenols
AMP-activated protein kinase (AMPK)
3-desoxy-7-KETO-DHEA
apple cider vinegar
avocado
Alpha methyl tetradecylthioacetic acid
beta-hydroxybutyrate
Berberis (unspecified)
chia seed
capric acid
cardarine
carqueja
capsinoids
coconut oil
coriander
capsaicin
capsiate
cha de bugre
diacylglycerol
dihydrocapsiate
evodiamine
ephedrine
flavanones
fucoxanthin
forskolin
grains of paradise
gymnemic acids
Higenamine
isomaltulose
lipstatin
Legume protein
macadamia
Monounsaturated fat
oolong tea
Oleoylethanolamide
phaseolamin
Palatinose
Perperine
Pinolenic acid
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
Ursolic Acid
Wakame
Walnut
Yohimbine
Other health conditions supported by bile salt
Acid IndigestionAppetite (deficient)
Digestion (poor)
Fat Metabolism (poor)
Gall Bladder (sluggish or removed)
Gall Stones
Gas and Bloating
Indigestion
Liver Detoxification