Evidence supporting the use of: Diacylglycerol
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Diacylglycerol (DAG) is a glyceride consisting of two fatty acid chains covalently bonded to a glycerol molecule. It is used in some functional foods and dietary supplements, primarily in Japan, for its potential to influence fat metabolism. The scientific rationale for using DAG stems from studies showing that dietary oils rich in diacylglycerol, as opposed to the more common triacylglycerol (TAG), may be metabolized differently in the body. Clinical studies, particularly randomized controlled trials, have reported that DAG oil consumption can lead to greater postprandial fat oxidation and lower postprandial triglyceride levels compared to TAG oil. Some studies also suggest long-term DAG oil intake may modestly reduce body weight and fat accumulation in overweight or obese individuals. The proposed mechanism is that DAG is more readily used as an energy source and less likely to be stored as body fat due to differences in its absorption and subsequent metabolic processing.
However, while there is a scientific basis and some clinical evidence, the overall effect size appears modest and not universally observed. Regulatory agencies such as the FDA have not approved DAG oil for the treatment of poor fat metabolism or obesity, and some studies report no significant benefit. Thus, the evidence is supportive but not strong, leading to a mid-level rating.
Other ingredients used for Fat Metabolism (poor)
3-desoxy-7-KETO-DHEA7-Keto-DHEA
Acetyl L-carnitine
Alpha methyl tetradecylthioacetic acid
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
anchovies
apple cider vinegar
artichoke
avocado
barberry
Berberis (unspecified)
beta-hydroxybutyrate
bile salt
biotin
black ginger
capric acid
capsaicin
capsaicinoids
capsiate
capsinoids
cardarine
carqueja
cha de bugre
chia seed
choline
cinnamon
coconut oil
Coleus forskohlii
conjugated linoleic acid (CLA)
coriander
dandelion
diacylglycerol
dihydrocapsiate
ephedrine
epigallocatechin gallate (EGCG)
evodiamine
fenugreek
flavanones
flavonols
forskohlii root
forskolin
fucoxanthin
garcinia
ginger
glucomannan
grains of paradise
guggul
gymnemic acids
hesperetin
Higenamine
hydroxycitric acid
isomaltulose
kelp
l-carnitine
lecithin
Legume protein
linoleic acid (LA)
lipase
lipstatin
macadamia
medium chain triglycerides (MCT)
Milk thistle
Monounsaturated fat
Oleoylethanolamide
omega-3 fatty acids
omega-7 fatty acids
oolong tea
Palatinose
palmitate
pantethine
Perperine
phaseolamin
phospholipids
Pinolenic acid
polyphenols
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
turmeric
Ursolic Acid
vitamin B
Wakame
Walnut
Yohimbine
Zinc
Other health conditions supported by diacylglycerol
Cholesterol (high)Fat Metabolism (poor)
Weight Loss
