Evidence supporting the use of: Glucomannan
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Glucomannan is a soluble dietary fiber extracted from the root of the konjac plant (Amorphophallus konjac). Its use in supporting fat metabolism is primarily based on scientific studies rather than traditional medicine. Glucomannan is believed to aid weight management and, indirectly, fat metabolism by promoting satiety, reducing appetite, and slowing the absorption of dietary fat and carbohydrates. Some clinical trials have shown that supplementation with glucomannan, when combined with a calorie-restricted diet, can lead to modest reductions in body weight and body fat. A few studies suggest that glucomannan may help lower total cholesterol and LDL cholesterol, markers often associated with fat metabolism and cardiovascular risk.
However, the mechanism is not a direct effect on fat metabolism per se, but rather an indirect one through its impact on dietary intake and nutrient absorption. The European Food Safety Authority (EFSA) has approved glucomannan for weight loss in the context of an energy-restricted diet, but the evidence for a direct effect on enhancing fat metabolism is limited. The overall quality of supporting evidence is moderate, with some meta-analyses showing small but significant effects and others indicating inconsistent results. Therefore, while there is some scientific validation for glucomannan’s role in weight management, its direct effect on fat metabolism is less well established, justifying a moderate evidence rating.
Other ingredients used for Fat Metabolism (poor)
7-Keto-DHEAAcetyl L-carnitine
alpha-linolenic acid (ALA)
anchovies
artichoke
barberry
biotin
canola oil
capsaicinoids
choline
cinnamon
Coleus forskohlii
conjugated linoleic acid (CLA)
turmeric
dandelion
epigallocatechin gallate (EGCG)
fenugreek
flavonols
forskohlii root
garcinia
ginger
glucomannan
guggul
hesperetin
hydroxycitric acid
kelp
l-carnitine
lecithin
linoleic acid (LA)
lipase
medium chain triglycerides (MCT)
Milk thistle
omega-3 fatty acids
omega-7 fatty acids
palmitate
pantethine
phospholipids
black ginger
vitamin B
Zinc
bile salt
polyphenols
AMP-activated protein kinase (AMPK)
3-desoxy-7-KETO-DHEA
apple cider vinegar
avocado
Alpha methyl tetradecylthioacetic acid
beta-hydroxybutyrate
Berberis (unspecified)
chia seed
capric acid
cardarine
carqueja
capsinoids
coconut oil
coriander
capsaicin
capsiate
cha de bugre
diacylglycerol
dihydrocapsiate
evodiamine
ephedrine
flavanones
fucoxanthin
forskolin
grains of paradise
gymnemic acids
Higenamine
isomaltulose
lipstatin
Legume protein
macadamia
Monounsaturated fat
oolong tea
Oleoylethanolamide
phaseolamin
Palatinose
Perperine
Pinolenic acid
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
Ursolic Acid
Wakame
Walnut
Yohimbine
Other health conditions supported by glucomannan
Appetite (excessive)Cholesterol (high)
Diabetes
Fat Metabolism (poor)
Indigestion
Metabolic Syndrome
Sugar Cravings
Triglycerides (high)
Weight Loss
Products containing glucomannan
Vitabase
7 Day Colon Cleanse
Douglas Laboratories
Fiber-Plex ™
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™ Detox Program
Designs For Health
PaleoCleanse Plus™Chocolate Detox Kit
Designs For Health
Plant Protein Cleanse Plus™ 570g
Pure Encapsulations
PureLean® Fiber