Evidence supporting the use of: Milk thistle
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Milk thistle (Silybum marianum) has a long history of traditional use, particularly for liver health and related metabolic functions. In many traditional systems, such as European herbal medicine, milk thistle seeds have been used for centuries to "cleanse" or "detoxify" the liver, which is central to various metabolic processes, including fat metabolism. The active component, silymarin, is believed to have hepatoprotective effects, supporting the liver's role in breaking down fats and removing toxins. Some traditional practices associate improved liver function with better fat metabolism, though this linkage is based more on holistic or empirical observation than on modern biomedical understanding.
Scientific evidence for milk thistle's direct effect on fat metabolism is limited. While there are some animal and in vitro studies suggesting that silymarin may influence lipid profiles and fat accumulation in the liver, high-quality human trials are scarce. Most research focuses on its ability to protect against liver damage rather than specifically improving poor fat metabolism. Therefore, while the traditional use of milk thistle for general liver and metabolic health is well documented, robust scientific evidence supporting its efficacy for directly treating poor fat metabolism is lacking. Thus, its use for this purpose is justified by tradition, with a moderate (2/5) evidence rating based on limited supportive data.
Other ingredients used for Fat Metabolism (poor)
7-Keto-DHEAAcetyl L-carnitine
alpha-linolenic acid (ALA)
anchovies
artichoke
barberry
biotin
canola oil
capsaicinoids
choline
cinnamon
Coleus forskohlii
conjugated linoleic acid (CLA)
turmeric
dandelion
epigallocatechin gallate (EGCG)
fenugreek
flavonols
forskohlii root
garcinia
ginger
glucomannan
guggul
hesperetin
hydroxycitric acid
kelp
l-carnitine
lecithin
linoleic acid (LA)
lipase
medium chain triglycerides (MCT)
Milk thistle
omega-3 fatty acids
omega-7 fatty acids
palmitate
pantethine
phospholipids
black ginger
vitamin B
Zinc
bile salt
polyphenols
AMP-activated protein kinase (AMPK)
3-desoxy-7-KETO-DHEA
apple cider vinegar
avocado
Alpha methyl tetradecylthioacetic acid
beta-hydroxybutyrate
Berberis (unspecified)
chia seed
capric acid
cardarine
carqueja
capsinoids
coconut oil
coriander
capsaicin
capsiate
cha de bugre
diacylglycerol
dihydrocapsiate
evodiamine
ephedrine
flavanones
fucoxanthin
forskolin
grains of paradise
gymnemic acids
Higenamine
isomaltulose
lipstatin
Legume protein
macadamia
Monounsaturated fat
oolong tea
Oleoylethanolamide
phaseolamin
Palatinose
Perperine
Pinolenic acid
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
Ursolic Acid
Wakame
Walnut
Yohimbine
Other health conditions supported by Milk thistle
Abdominal PainAddictions (general remedies for)
Alcoholism
Cancer Treatment (reducing side effects)
Chemical Poisoning
Chemotherapy (reducing side effects)
Cirrhosis of the Liver
Environmental Pollution
Fat Metabolism (poor)
Fatty Liver Disease
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Hangover
Heavy Metal Poisoning
Hepatitis
Jaundice (adults)
Liver Detoxification
Poisoning (general)
Products containing Milk thistle
Pure Encapsulations
AntiOxidant Formula
Metagenics
Axis Endo™ Mango
Integrative Therapeutics
Detoxication Factors
Integrative Therapeutics
Detoxication Factors
Pure Encapsulations
Digestion GB
Pure Encapsulations
Digestion GB
Pure Encapsulations
DIM Detox
Designs For Health
Hepatatone Plus™
Vitabase
Life's Essentials Plus
Designs For Health
Liposomal B Supreme
Integrative Therapeutics
Lipotropic Complex
Pure Encapsulations
Lipotropic Detox
Thorne
Liver Cleanse
Pure Encapsulations
Liver G.I. Detox
Designs For Health
LV-GB Complex™
Pure Encapsulations
LVR Formula
Pure Encapsulations
LVR Formula
Thorne
MediClear Plus
Designs For Health
Milk Thistle
Douglas Laboratories
Milk Thistle Max-V
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™ Detox Program
Designs For Health
PaleoCleanse Plus™Chocolate Detox Kit
Metagenics
PhytoGanix® Tropical Fruit
Designs For Health
Plant Protein Cleanse
Designs For Health
Plant Protein Cleanse Plus™ 570g
Thorne
S.A.T.
Thorne
Siliphos Milk Thistle
Pure Encapsulations
Silymarin
Pure Encapsulations
Silymarin
Metagenics
Silymarin 80™
Douglas Laboratories
Silymarin/Milk Thistle Extract
Pure Encapsulations
SP Ultimate
Pure Encapsulations
SP Ultimate
Integrative Therapeutics
Super Milk Thistle X
Pure Encapsulations
Ultra Pure Pack
Pure Encapsulations
UltraDetox 10-Day Pure Pack
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Vitabase
Vision Support