Evidence supporting the use of: Milk thistle
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Milk thistle (Silybum marianum) has a long history of traditional use, particularly for liver health and related metabolic functions. In many traditional systems, such as European herbal medicine, milk thistle seeds have been used for centuries to "cleanse" or "detoxify" the liver, which is central to various metabolic processes, including fat metabolism. The active component, silymarin, is believed to have hepatoprotective effects, supporting the liver's role in breaking down fats and removing toxins. Some traditional practices associate improved liver function with better fat metabolism, though this linkage is based more on holistic or empirical observation than on modern biomedical understanding.
Scientific evidence for milk thistle's direct effect on fat metabolism is limited. While there are some animal and in vitro studies suggesting that silymarin may influence lipid profiles and fat accumulation in the liver, high-quality human trials are scarce. Most research focuses on its ability to protect against liver damage rather than specifically improving poor fat metabolism. Therefore, while the traditional use of milk thistle for general liver and metabolic health is well documented, robust scientific evidence supporting its efficacy for directly treating poor fat metabolism is lacking. Thus, its use for this purpose is justified by tradition, with a moderate (2/5) evidence rating based on limited supportive data.
Other ingredients used for Fat Metabolism (poor)
3-desoxy-7-KETO-DHEA7-Keto-DHEA
Acetyl L-carnitine
Alpha methyl tetradecylthioacetic acid
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
anchovies
apple cider vinegar
artichoke
avocado
barberry
Berberis (unspecified)
beta-hydroxybutyrate
bile salt
biotin
black ginger
capric acid
capsaicin
capsaicinoids
capsiate
capsinoids
cardarine
carqueja
cha de bugre
chia seed
choline
cinnamon
coconut oil
Coleus forskohlii
conjugated linoleic acid (CLA)
coriander
dandelion
diacylglycerol
dihydrocapsiate
ephedrine
epigallocatechin gallate (EGCG)
evodiamine
fenugreek
flavanones
flavonols
forskohlii root
forskolin
fucoxanthin
garcinia
ginger
glucomannan
grains of paradise
guggul
gymnemic acids
hesperetin
Higenamine
hydroxycitric acid
isomaltulose
kelp
l-carnitine
lecithin
Legume protein
linoleic acid (LA)
lipase
lipstatin
macadamia
medium chain triglycerides (MCT)
Milk thistle
Monounsaturated fat
Oleoylethanolamide
omega-3 fatty acids
omega-7 fatty acids
oolong tea
Palatinose
palmitate
pantethine
Perperine
phaseolamin
phospholipids
Pinolenic acid
polyphenols
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
turmeric
Ursolic Acid
vitamin B
Wakame
Walnut
Yohimbine
Zinc
Other health conditions supported by Milk thistle
Abdominal PainAddictions (general remedies for)
Alcoholism
Cancer Treatment (reducing side effects)
Chemical Poisoning
Chemotherapy (reducing side effects)
Cirrhosis of the Liver
Environmental Pollution
Fat Metabolism (poor)
Fatty Liver Disease
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Hangover
Heavy Metal Poisoning
Hepatitis
Jaundice (adults)
Liver Detoxification
Poisoning (general)
Products containing Milk thistle
Pure Encapsulations
AntiOxidant Formula
Metagenics
Axis Endo™ Mango
Integrative Therapeutics
Detoxication Factors
Integrative Therapeutics
Detoxication Factors
Pure Encapsulations
Digestion GB
Pure Encapsulations
Digestion GB
Pure Encapsulations
DIM Detox
Designs For Health
Hepatatone Plus™
Vitabase
Life's Essentials Plus
Designs For Health
Liposomal B Supreme
Integrative Therapeutics
Lipotropic Complex
Pure Encapsulations
Lipotropic Detox
Thorne
Liver Cleanse
Pure Encapsulations
Liver G.I. Detox
Designs For Health
LV-GB Complex™
Pure Encapsulations
LVR Formula
Pure Encapsulations
LVR Formula
Thorne
MediClear Plus
Designs For Health
Milk Thistle
Douglas Laboratories
Milk Thistle Max-V
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™ Detox Program
Designs For Health
PaleoCleanse Plus™Chocolate Detox Kit
Metagenics
PhytoGanix® Tropical Fruit
Designs For Health
Plant Protein Cleanse
Designs For Health
Plant Protein Cleanse Plus™ 570g
Thorne
S.A.T.
Thorne
Siliphos Milk Thistle
Pure Encapsulations
Silymarin
Pure Encapsulations
Silymarin
Metagenics
Silymarin 80™
Douglas Laboratories
Silymarin/Milk Thistle Extract
Pure Encapsulations
SP Ultimate
Pure Encapsulations
SP Ultimate
Integrative Therapeutics
Super Milk Thistle X
Pure Encapsulations
Ultra Pure Pack
Pure Encapsulations
UltraDetox 10-Day Pure Pack
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Vitabase
Vision Support
