Evidence supporting the use of: Palmitate
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Palmitate, specifically in the form of palmitic acid or as a palmitate ester (e.g., ascorbyl palmitate), is a saturated fatty acid commonly found in both dietary sources and endogenous human metabolism. Its use in supporting or treating "poor fat metabolism" is primarily grounded in its role as a substrate in fatty acid oxidation pathways. In human physiology, palmitate is one of the principal fatty acids oxidized for energy during periods of fasting or increased energy demand. Some scientific studies have explored the metabolism of palmitate in the context of metabolic disorders, such as obesity or insulin resistance, noting that impaired oxidation of palmitate may be associated with these conditions. However, direct supplementation with palmitate to "support" fat metabolism is not widely validated or recommended in clinical guidelines. Most evidence comes from mechanistic or cellular studies, which show how palmitate is metabolized, rather than from clinical trials demonstrating a therapeutic effect in people with poor fat metabolism. In fact, excessive palmitate intake (as found in high saturated fat diets) is often associated with negative metabolic outcomes rather than improvement. Therefore, while there is a scientific basis for studying palmitate in the context of fat metabolism, there is limited clinical evidence supporting its direct use as a supplement for this purpose.
Other ingredients used for Fat Metabolism (poor)
7-Keto-DHEAAcetyl L-carnitine
alpha-linolenic acid (ALA)
anchovies
artichoke
barberry
biotin
canola oil
capsaicinoids
choline
cinnamon
Coleus forskohlii
conjugated linoleic acid (CLA)
turmeric
dandelion
epigallocatechin gallate (EGCG)
fenugreek
flavonols
forskohlii root
garcinia
ginger
glucomannan
guggul
hesperetin
hydroxycitric acid
kelp
l-carnitine
lecithin
linoleic acid (LA)
lipase
medium chain triglycerides (MCT)
Milk thistle
omega-3 fatty acids
omega-7 fatty acids
palmitate
pantethine
phospholipids
black ginger
vitamin B
Zinc
bile salt
polyphenols
AMP-activated protein kinase (AMPK)
3-desoxy-7-KETO-DHEA
apple cider vinegar
avocado
Alpha methyl tetradecylthioacetic acid
beta-hydroxybutyrate
Berberis (unspecified)
chia seed
capric acid
cardarine
carqueja
capsinoids
coconut oil
coriander
capsaicin
capsiate
cha de bugre
diacylglycerol
dihydrocapsiate
evodiamine
ephedrine
flavanones
fucoxanthin
forskolin
grains of paradise
gymnemic acids
Higenamine
isomaltulose
lipstatin
Legume protein
macadamia
Monounsaturated fat
oolong tea
Oleoylethanolamide
phaseolamin
Palatinose
Perperine
Pinolenic acid
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
Ursolic Acid
Wakame
Walnut
Yohimbine