Evidence supporting the use of: Palmitate
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Palmitate, specifically in the form of palmitic acid or as a palmitate ester (e.g., ascorbyl palmitate), is a saturated fatty acid commonly found in both dietary sources and endogenous human metabolism. Its use in supporting or treating "poor fat metabolism" is primarily grounded in its role as a substrate in fatty acid oxidation pathways. In human physiology, palmitate is one of the principal fatty acids oxidized for energy during periods of fasting or increased energy demand. Some scientific studies have explored the metabolism of palmitate in the context of metabolic disorders, such as obesity or insulin resistance, noting that impaired oxidation of palmitate may be associated with these conditions. However, direct supplementation with palmitate to "support" fat metabolism is not widely validated or recommended in clinical guidelines. Most evidence comes from mechanistic or cellular studies, which show how palmitate is metabolized, rather than from clinical trials demonstrating a therapeutic effect in people with poor fat metabolism. In fact, excessive palmitate intake (as found in high saturated fat diets) is often associated with negative metabolic outcomes rather than improvement. Therefore, while there is a scientific basis for studying palmitate in the context of fat metabolism, there is limited clinical evidence supporting its direct use as a supplement for this purpose.
Other ingredients used for Fat Metabolism (poor)
3-desoxy-7-KETO-DHEA7-Keto-DHEA
Acetyl L-carnitine
Alpha methyl tetradecylthioacetic acid
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
anchovies
apple cider vinegar
artichoke
avocado
barberry
Berberis (unspecified)
beta-hydroxybutyrate
bile salt
biotin
black ginger
capric acid
capsaicin
capsaicinoids
capsiate
capsinoids
cardarine
carqueja
cha de bugre
chia seed
choline
cinnamon
coconut oil
Coleus forskohlii
conjugated linoleic acid (CLA)
coriander
dandelion
diacylglycerol
dihydrocapsiate
ephedrine
epigallocatechin gallate (EGCG)
evodiamine
fenugreek
flavanones
flavonols
forskohlii root
forskolin
fucoxanthin
garcinia
ginger
glucomannan
grains of paradise
guggul
gymnemic acids
hesperetin
Higenamine
hydroxycitric acid
isomaltulose
kelp
l-carnitine
lecithin
Legume protein
linoleic acid (LA)
lipase
lipstatin
macadamia
medium chain triglycerides (MCT)
Milk thistle
Monounsaturated fat
Oleoylethanolamide
omega-3 fatty acids
omega-7 fatty acids
oolong tea
Palatinose
palmitate
pantethine
Perperine
phaseolamin
phospholipids
Pinolenic acid
polyphenols
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
turmeric
Ursolic Acid
vitamin B
Wakame
Walnut
Yohimbine
Zinc
