Evidence supporting the use of: Tetradecylthioacetic acid
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Tetradecylthioacetic acid (TTA) is a synthetic fatty acid that has been studied primarily in animal models and limited human trials for its potential effects on lipid metabolism. TTA is known to act as a peroxisome proliferator-activated receptor (PPAR) agonist, particularly influencing PPAR-alpha, which plays a role in regulating genes involved in fatty acid oxidation and energy homeostasis. Preclinical studies in rodents have demonstrated that TTA can enhance fatty acid oxidation, reduce plasma triglycerides, and improve lipid profiles, suggesting a beneficial effect on fat metabolism. Small-scale human studies, such as those in patients with type 2 diabetes and metabolic syndrome, have shown modest improvements in lipid parameters, including some reduction in plasma triglyceride levels. However, results are inconsistent and the overall clinical significance remains unclear.
Despite encouraging preclinical data, evidence in humans is limited both in quality and quantity. There are no large-scale randomized controlled trials that confirm its efficacy for improving fat metabolism or treating related metabolic disorders. As a result, while there is a scientific basis for the use of TTA in supporting fat metabolism, the current level of evidence supporting its clinical use in humans is low to moderate at best. Further research is needed to determine its safety, efficacy, and potential therapeutic role in humans with poor fat metabolism.
More about Tetradecylthioacetic acid
More about Fat Metabolism (poor)
Other ingredients used for Fat Metabolism (poor)
3-desoxy-7-KETO-DHEA7-Keto-DHEA
Acetyl L-carnitine
Alpha methyl tetradecylthioacetic acid
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
anchovies
apple cider vinegar
artichoke
avocado
barberry
Berberis (unspecified)
beta-hydroxybutyrate
bile salt
biotin
black ginger
capric acid
capsaicin
capsaicinoids
capsiate
capsinoids
cardarine
carqueja
cha de bugre
chia seed
choline
cinnamon
coconut oil
Coleus forskohlii
conjugated linoleic acid (CLA)
coriander
dandelion
diacylglycerol
dihydrocapsiate
ephedrine
epigallocatechin gallate (EGCG)
evodiamine
fenugreek
flavanones
flavonols
forskohlii root
forskolin
fucoxanthin
garcinia
ginger
glucomannan
grains of paradise
guggul
gymnemic acids
hesperetin
Higenamine
hydroxycitric acid
isomaltulose
kelp
l-carnitine
lecithin
Legume protein
linoleic acid (LA)
lipase
lipstatin
macadamia
medium chain triglycerides (MCT)
Milk thistle
Monounsaturated fat
Oleoylethanolamide
omega-3 fatty acids
omega-7 fatty acids
oolong tea
Palatinose
palmitate
pantethine
Perperine
phaseolamin
phospholipids
Pinolenic acid
polyphenols
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
turmeric
Ursolic Acid
vitamin B
Wakame
Walnut
Yohimbine
Zinc
Other health conditions supported by Tetradecylthioacetic acid
Cholesterol (high)Fat Metabolism (poor)
Fatty Liver Disease
Metabolic Syndrome
Triglycerides (high)
