Evidence supporting the use of: Ursolic Acid
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Ursolic acid is a natural compound found in various plants and herbs, including apple peels, rosemary, and basil. Its use for supporting or improving fat metabolism is based on emerging scientific evidence, primarily from preclinical studies. Animal studies have shown that ursolic acid supplementation can reduce diet-induced obesity, enhance energy expenditure, increase skeletal muscle, and decrease fat mass. These effects are thought to be mediated by the activation of pathways involved in muscle growth (such as IGF-1 signaling) and increased brown fat thermogenesis, which can lead to greater calorie burning.
Human data on ursolic acid’s effects on fat metabolism are limited. Some small clinical trials and pilot studies suggest that ursolic acid may increase muscle mass and decrease body fat when combined with resistance training. However, these studies are preliminary, often with small sample sizes and short durations. The overall body of evidence supporting ursolic acid's role in fat metabolism is still developing, with most of the supportive data coming from animal models and in vitro experiments.
In summary, the use of ursolic acid to support fat metabolism is justified by early scientific investigation, but robust, large-scale clinical trials are lacking. Therefore, while there is a scientific rationale and some preliminary evidence, the strength of the evidence remains moderate to low at this time.
Other ingredients used for Fat Metabolism (poor)
7-Keto-DHEAAcetyl L-carnitine
alpha-linolenic acid (ALA)
anchovies
artichoke
barberry
biotin
canola oil
capsaicinoids
choline
cinnamon
Coleus forskohlii
conjugated linoleic acid (CLA)
turmeric
dandelion
epigallocatechin gallate (EGCG)
fenugreek
flavonols
forskohlii root
garcinia
ginger
glucomannan
guggul
hesperetin
hydroxycitric acid
kelp
l-carnitine
lecithin
linoleic acid (LA)
lipase
medium chain triglycerides (MCT)
Milk thistle
omega-3 fatty acids
omega-7 fatty acids
palmitate
pantethine
phospholipids
black ginger
vitamin B
Zinc
bile salt
polyphenols
AMP-activated protein kinase (AMPK)
3-desoxy-7-KETO-DHEA
apple cider vinegar
avocado
Alpha methyl tetradecylthioacetic acid
beta-hydroxybutyrate
Berberis (unspecified)
chia seed
capric acid
cardarine
carqueja
capsinoids
coconut oil
coriander
capsaicin
capsiate
cha de bugre
diacylglycerol
dihydrocapsiate
evodiamine
ephedrine
flavanones
fucoxanthin
forskolin
grains of paradise
gymnemic acids
Higenamine
isomaltulose
lipstatin
Legume protein
macadamia
Monounsaturated fat
oolong tea
Oleoylethanolamide
phaseolamin
Palatinose
Perperine
Pinolenic acid
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
Ursolic Acid
Wakame
Walnut
Yohimbine
Other health conditions supported by Ursolic Acid
Alzheimer's DiseaseArthritis
Body Building
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Diabetes
Fat Metabolism (poor)
Fatty Liver Disease
Inflammation
Liver Detoxification
Muscle Tone (lack of)
Osteoporosis
Rheumatoid Arthritis
Triglycerides (high)
Wrinkles