Relationship: Fatigue and vitamin C

Evidence supporting the use of: Vitamin C
For the health condition: Fatigue

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Synopsis
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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid) is sometimes used to support or treat fatigue, but the scientific evidence supporting this use is limited. While vitamin C is essential for many bodily functions, including immune support and the synthesis of neurotransmitters such as norepinephrine, its direct impact on fatigue is not robustly established in the general population. Some small studies and clinical observations have suggested that vitamin C supplementation may reduce feelings of fatigue, particularly in individuals who are vitamin C deficient or under significant physical stress (such as athletes or hospitalized patients). For example, a few studies have shown that high-dose intravenous vitamin C can reduce fatigue in cancer patients or those with certain chronic illnesses. However, these effects do not necessarily translate to the general healthy population.

Most clinical trials have found that vitamin C supplementation in individuals with adequate baseline levels does not significantly reduce fatigue or improve energy levels. The rationale for its use is partially based on the role of vitamin C in adrenal gland function and the synthesis of carnitine, a molecule involved in energy production. However, for most people, a balanced diet provides sufficient vitamin C, and deficiency is rare in developed countries.

In summary, while there is some scientific rationale and limited clinical evidence supporting vitamin C for fatigue in specific populations (such as those with deficiency or chronic illness), overall evidence is weak. Thus, its routine use for fatigue in healthy individuals is not strongly supported by scientific research.

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Other ingredients used for Fatigue

1,3,7-Trimethylpurine-2,6-dione
5-methyltetrahydrofolate glucosamine
Acai berry
Acetyl L-carnitine
Acetyl-L-Tyrosine
Achyranthes
Adenophora
adenosine 5-triphosphate disodium (ATP)
Adenosine triphosphate (ATP)
adrenal cortex
Adzuki bean
Agarwood
Agrimonia pilosa
AHCC
Akebia
Albizia
Aletris
Alfalfa
Algae
Algal protein
Allium tuberosum
Almond fruit
Alpha D-ribofuranose
Alpha lactalbumin
Alpha polylactate
alpha-ketoglutarate (AKG)
alpha-lipoic acid
amaranth
amber
American Liverleaf
amino acids
Amor seco
anamu
anemarrhena asphodeloides
Angelica
animal protein
anthocyanins
antler
Antrodia camphorata
apple
apple cider vinegar
Aralia
Ardisia
Areca
Arginine aspartate
arginine creatine
Arginine malate
Arginine orotate
Arisaema
arjun tree
arjuna
arjunic acid
Armillaria mellea
ashitaba
ashwagandha
asparagus
aspartic acid
astaxanthin
aster root
astragaloside
astragalus
atractylodes
atractylone
Autumn Olive
avens
ba ji tian
baccosides
bacoside
bacteria
baicalin
banana
baobab
barley
Basidiomycota
Bassia scoparia
Bauhinia
BCAA
bee pollen
beef
Beef liver
beet
bergamot
beta-alanine
beta-hydroxybutyrate
betel
betony
Bifidobacterium breve
big quaking grass
bignay
biota seed
bird\'s nest
black cumin
black garlic
black ginger
black gram
black salt
black seed
black tea
Blepharis
Blue-Green Alage
Boerhavia diffusa
bone marrow
bonito peptide
Borassus aethiopum
borassus palm
borneol
bottle gourd
bovine heart
bovine kidney
bovine liver
bovine spleen
brahmi
branched-chain amino acids
breadnut
Broussonetia
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bupleurum falcatum
burdock
C-phycocyanin
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caffeine
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cardamom
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catalpol
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catuaba
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cereal grass
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chaga mushroom
chanterelle
chard
chen pi
chestnut
chia seed
chia seed
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chlorella
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chokeberry
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chuchuhuasi
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coca
cocarboxylase
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coenzyme Q10 (CoQ10)
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cordyceps
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cumin
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date
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dioscorea
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dodder
dodeca-2E, 4E-dienoic acid isobutylamide
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dragonhead
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dulse leaf
durian
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electrolytes blend (proprietary)
eleuthero
elk antler
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emblicanin
enokitake
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ephedrine
ergothioneine
eriocitrin
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eurycomanone
fatty acids
fennel
fenugreek
fenuside
finger-leaf morning glory
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fish protein
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flat-stem milk-vetch
flavin mononucleotide
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folate
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fruit and vegetable blend (proprietary)
fu ling
fulvic acid
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horny goat weed
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hydroxymethylbutyrate
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hypsizygus marmoreus
icariin
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iridoid glycosides
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l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-alanyl-L-glutamine
l-carnitine
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lactiplantibacillus plantarum
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NADH
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nicotinamide riboside
noni
nopal
nut grass
oat
okra
omega-3 fatty acids
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oolong tea
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ophiopogon root
orange
orchid
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ornithine alpha-ketoglutarate
ornithine L-aspartic acid
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oryza
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oxaloacetic acid
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oyster mushroom
paeoniflorin
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pantothenic acid (vitamin B5)
paraxanthine
parsley
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peony
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phellodendron amurense
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plum fruit
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polyporous mushroom
polysaccharides
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potassium
prebiotic blend (proprietary)
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protein
prune
Pseudostellaria
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punarnava
purslane
Pycnogenol
pyrroloquinoline disodium salt
pyrroloquinoline quinone
pyruvate
quail egg
quercetin
quinoa
Quinoa Protein
Rehmannia
rehmannia glutinosa
reishi mushroom
relora® (proprietary)
Rhaponticum
Rhodiola
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riboflavin (vitamin B2)
ribose
rice
robusta coffee
rockweed
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root tuber
Rosa roxburghii
Rosabin
rosavins
rosemary
royal jelly
Rubia cordifolia
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saponins
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sarsaparilla
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scrophularia root
sea salt
seaweed
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sesame
Sete sangrias
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shiitake mushroom
Shilajit
Sichuan Lovage
Sida cordifolia
silk tree
Silkmoth
smilax
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soursop
Spanish Needle
Spantholobus
Spelt
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spinach
spirulina
spruce
Sulbutiamine
suma
Sumac
Sweet Bay
Sweet Orange alcohol
Sword Bean
Tamarind
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Thiamin (vitamin B1)
thyroid substance
Tiger Nut
Tinospora cordifolia
Tongkat ali
trace minerals
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Trichilia catigua
Trichopus zeylanicus
Trimethylglycine (TMG)
Triphala
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turmeric
Turtle Head
ubiquinol
Uncaria
Urolithin A
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
Vegetable Protein
velvet bean
Vetiver
Vine tea
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
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Wax Gourd
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wheat germ
wheat grass
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whole adrenal glandular
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Xanthine
Xanthone
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Xylaria nigripes
Yeast
Yerba buena
Yerba mate
Yohimbine
Yuzu
Zapilopatle Bean
Zedoary
Zucchini
β-nicotinamide mononucleotide (NMN)

Other health conditions supported by vitamin C

Abrasions
Abscesses
Acne
Acquired Immune Deficiency Syndrome
Addictions (general remedies for)
Addison's Disease
Adrenal Fatigue
Age Spots
Aging (prevention)
Alcoholism
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Anal Fistula or Fissure
Anemia
Antibiotics (alternatives to)
Antibiotics (side effects of)
Anxiety
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Autism
Autoimmune Disorders
Bell's Palsy
Bites and Stings
Bladder Infection
Bleeding (external)
Bleeding (internal)
Blood Poisoning
Boils
Bronchitis
Bruises (healing)
Bruises (prevention)
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Capillary Weakness
Carbuncles
Cardiovascular Disease
Cartilage Damage
Cataracts
Cervical Dysplasia
Chemical Poisoning
Chemotherapy (reducing side effects)
Chicken Pox
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colon (atonic)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Conjunctivitis
Contagious Diseases
Convalescence
Copper Toxicity
Cough (dry)
Cough (general)
Cuts
Cystic Breast Disease
Cystic Fibrosis
Debility
Dementia
Denture Sores
Depression
Diabetes
Diabetic Retinopathy
Environmental Pollution
Epstein Barr Virus
Eye Problems
Eyesight (poor)
Fatigue
Fatty Liver Disease
Free Radical Damage
Gall Stones
Gastritis
Gingivitis
Glaucoma
Gonorrhea
Gout
Hair (loss or thinning)
Hair Care (general)
Heart (weakness)
Heavy Metal Poisoning
Hemorrhoids
Hepatitis
Herpes
Hot Flashes
Hypertension
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Knees (weak)
Laryngitis
Lead Poisoning
Lesions
Leucorrhea
Leukemia
Ligaments (torn or injured)
Liver Detoxification
Lyme Disease
Macular Degeneration
Mastitis
Measles
Memory and Brain Function
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Metabolic Syndrome
Mononucleosis
Mumps
Nose Bleeds
Oral Surgery
Osteoporosis
Pancreatitis
PMS (general)
PMS Type C
PMS Type H
Pneumonia
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Prolapsed Uterus
Prostatitis
Radiation Sickness
Rashes and Hives
Restless Leg Syndrome
Rheumatoid Arthritis
Rhinitis
Rhinitis, Allergic
Rosacea
Scars / Scar Tissue
Schizophrenia
Scratches and Abrasions
Scurvy
Shingles
Shock
Sinus Infection
Skin (infections)
Skin Care (general)
Sore Throat
Spider Veins
Spinal Disks
Sprains
Strep Throat
Stretch Marks
Sunburn
Surgery (healing from)
Surgery (preparation for)
Teeth (loose)
Tendonitis
Thrush
Tickle in Throat
Tonsillitis
Tooth Extraction
Toxemia
Triglycerides (high)
Tuberculosis
Ulcerations (external)
Ulcers
Uric Acid Retention
Urinary Tract Infections
Vaginitis
Varicose Veins
Warts
Wounds and Sores
Wrinkles

Products containing vitamin C

Health Concerns

Brands

Evidence supporting the use of: Vitamin C
For the health condition: Fatigue

Table of Contents

Synopsis

Other ingredients used for Fatigue

Other health conditions supported by vitamin C

Products containing vitamin C

Health Concerns

Brands

Evidence supporting the use of: Vitamin CFor the health condition: Fatigue

Table of Contents

Synopsis

Other ingredients used for Fatigue

Other health conditions supported by vitamin C

Products containing vitamin C

Evidence supporting the use of: Vitamin C
For the health condition: Fatigue