Evidence supporting the use of: Algae
For the health condition: Fatty Liver Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Algae, particularly certain species such as Spirulina and Chlorella, have been investigated for their potential role in supporting or treating non-alcoholic fatty liver disease (NAFLD). The scientific justification stems from several animal and limited human studies suggesting that algae-derived compounds may help reduce hepatic fat accumulation, inflammation, and oxidative stress—core factors in the pathogenesis of fatty liver disease. Key components in algae, such as phycocyanin (from Spirulina), antioxidants, and polyunsaturated fatty acids, are believed to exert hepatoprotective effects.
For example, a 2013 animal study published in Lipids in Health and Disease showed that Spirulina supplementation reduced liver fat and improved lipid profiles in rats fed a high-fat diet. Small clinical trials have also indicated that Spirulina and Chlorella supplementation may reduce liver enzyme levels (ALT, AST) in patients with NAFLD, though the sample sizes are often small and methodologies vary.
Despite these promising findings, the overall quality of evidence remains moderate to low. Most studies are preclinical or involve small human cohorts, and the exact mechanisms are not fully elucidated. Larger, well-designed clinical trials are needed before algae can be broadly recommended for fatty liver disease. Therefore, the evidence rating is 2: preliminary scientific support exists, but it is not yet robust or definitive.
Other ingredients used for Fatty Liver Disease
4-hydroxyisoleucine7,14-Hydroxy-Docosapentaenoic Acid
Acacetin
Adzuki bean
Akkermansia muciniphila
Algae
algal oil
Algal protein
Alisma
Alpha methyl tetradecylthioacetic acid
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
alpha-lipoic acid
AMP-activated protein kinase (AMPK)
ampelopsin
Anemarrhena
anemarrhena asphodeloides
anthocyanins
Antrodia camphorata
apigenin
apocynin
arabinoxylan
argan nut oil
arjun tree
arjuna
Arjunolic acid
Aronia melanocarpa
artichoke
Ascophyllum nodosum
ashitaba
astaxanthin
astragaloside
avocado
baicalein
baicalin
banaba
barberry
barley
beet
berberine
Berberis (unspecified)
betanin
Bifidobacteria
Bifidobacterium bifidum
Bifidobacterium longum
bile acid
black garlic
Blakeslea trispora
borotutu
branched-chain amino acids
Brassica
Brown Algae
brutieridin
butyrate triglyceride
butyric acid
camelina oil
carnosic acid
carqueja
catechins
caterpillar mushroom
Caulerpa okamurae
cauliflower
chebulic acid
chia seed
chicory
Chitin-Glucan Complex
chlorella
chlorogenic acid
chokeberry
choline
coix
conjugated linoleic acid (CLA)
copalchi
coriander
corilagin
corosolic acid
crocetin
cruciferous
Curcuma
curcumin
cyclodextrin
cynarin
cynaropicrin
D-Pinitol
dandelion
danshen
decursin
diallyl disulfide (DADS)
diallyl sulfide
dihydromyricetin
diosgenin
dithiolthiones
DL-Methionine
eicosapentaenoic acid
Enicostemma littorale
EPA (eicosapentaenoic acid)
epicatechin
epigallocatechin gallate (EGCG)
ergothioneine
eriocitrin
erythrodiol
Eucommia ulmoides
fatty acids
fenugreek
ferulic acid
fiber
fiber blend (proprietary)
fish oil
fish protein
flavanones
flavonolignan
flavonols
flaxseed
fucoidan
fucosterol
fucoxanthin
ganoderma
ginger
Glutathione
grape
hesperetin
hydroxycinnamic acid
hydroxytyrosol
isosilybin
Jaboticaba
jiaogulan
Job\'s tears
Jurubeba
Kefir
kelp
l-carnitine
L-glutathione
L-methionine
L-taurine
Lactobacillus plantarum
lecithin
Legume protein
licorice root
limonoid
lingzhi
liquid liver fractions
Lycium
mangiferin
Marine fat
Marine lipid
medium chain triglycerides (MCT)
Milk thistle
Monounsaturated fat
Morus
Mulberry
Myricetin
Naringenin
Naringin
Niacin (vitamin B3)
nicotinamide riboside
nopal
oleanolic acid
oleic acid
Oleoylethanolamide
Oleuropein
Oligosaccharides
olive
omega-3 fatty acids
omega-9 fatty acids
oolong tea
ornithine L-aspartic acid
Osthole
Oxymatrine
palmitoleic acid
perilla
Phaeophyceae
Phellodendron
phenolic compounds
phlorizin
phlorotannins
phosphatidylcholine
phospholipids
Phthalides
picrorhiza kurroa
Pinitol
Polydatin
polyphenols
prebiotic blend (proprietary)
psyllium
pu-er tea
Puerarin
punarnava
punicalagins
purple tea
rapeseed oil
Rebaudioside
reishi mushroom
resveratrol
rhubarb
S-allylcysteine
Salacia
Salvianolic acid
Schisandrins
Schizochytrium
Schizochytrium Oil
seaweed
sesame
Sesamin
Silybin
Silychristin
Silydianin
silymarin
Sinensetin
spirulina
Syringic acid
Tangeretin
Tanshinone
Taurine
Taxifolin
Tetradecylthioacetic acid
Theabrownin
Thistle
tocotrienols
Trans-pterostilbene
Trehalose
tributyrin
Trimethylglycine (TMG)
Triphala
turmeric
Tyrosol
Urolithin A
Ursolic Acid
Varuna
vitamin C
vitamin E
Wakame
Walnut
Wax Gourd
Yacon
Yin Chen
Zinc
Zucchini
β-nicotinamide mononucleotide (NMN)
Other health conditions supported by Algae
Aging (prevention)Alzheimer's Disease
Anemia
Antibiotics (alternatives to)
Appetite (deficient)
Arthritis
Athletic and Exercise Aids
Blood Clots (prevention of)
Body Building
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (to the brain)
Colds (general)
Colds (prevention)
Colitis
Constipation (adults)
Convalescence
Debility
Diabetes
Diarrhea
Digestion (poor)
Energy (lack of)
Fatigue
Fatty Liver Disease
Free Radical Damage
Gastritis
Goiter
Hair (loss or thinning)
Hangover
Heavy Metal Poisoning
Hepatitis
Hypertension
Inflammation
Inflammatory Bowel Disorders
Influenza
Irritable Bowel Syndrome
Liver Detoxification
Macular Degeneration
Memory and Brain Function
Metabolic Syndrome
Ulcers
Weight Loss
Wounds and Sores
