Evidence supporting the use of: Anthocyanin
For the health condition: Fatty Liver Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanins are a class of flavonoid compounds found in various fruits and vegetables, especially those with red, purple, or blue pigmentation (such as berries, red cabbage, and black rice). The potential use of anthocyanins in supporting or treating fatty liver disease (specifically non-alcoholic fatty liver disease, NAFLD) has been explored in a number of preclinical studies and a limited number of clinical trials. Evidence suggests that anthocyanins may exert beneficial effects on liver health through several mechanisms, including antioxidant activity, anti-inflammatory properties, and improvement of lipid metabolism.

Animal studies have shown that anthocyanin supplementation can reduce hepatic lipid accumulation, improve insulin sensitivity, and decrease markers of oxidative stress in models of diet-induced fatty liver disease. For example, studies in mice and rats have demonstrated that anthocyanins from sources like blueberries or black rice can attenuate the progression of NAFLD and improve liver enzyme levels. In vitro research also suggests anthocyanins can modulate pathways related to fat synthesis and inflammation within liver cells.

However, human evidence is relatively limited. Small-scale clinical trials and observational studies have reported potential improvements in liver enzyme levels and metabolic parameters after anthocyanin-rich dietary interventions, but sample sizes are small and methodological quality is often modest. There are currently no large, definitive randomized controlled trials confirming anthocyanins as an effective treatment for fatty liver disease in humans. Thus, while there is a scientific rationale and some preliminary evidence, the overall level of scientific validation is still considered weak to moderate (rated 2/5).

More about Anthocyanin
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Other ingredients used for Fatty Liver Disease

akkermansia muciniphila
algal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
arjun tree
artichoke
astaxanthin
banaba
barberry
barley
beet
berberine
bifidobacterium bifidum
bifidobacterium longum
black garlic
sesame
branched-chain amino acids
butyrate triglyceride
canola oil
catechins
caterpillar mushroom
cauliflower
chia seed
chicory
chlorella
chokeberry
choline
conjugated linoleic acid (CLA)
turmeric
curcumin
cyclodextrin
dandelion
diallyl disulfide (DADS)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fenugreek
fiber blend (proprietary)
fish oil
fish protein
flavonols
flaxseed
ginger
grape
hesperetin
kelp
l-carnitine
l-glutathione
l-methionine
l-taurine
lecithin
licorice root
liquid liver fractions
marine lipid
medium chain triglycerides (MCT)
milk thistle
naringin
niacin (vitamin B3)
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-9 fatty acids
palmitoleic acid
perilla
phenolic acids
phosphatidylcholine
phospholipids
prebiotic blend (proprietary)
butyric acid
psyllium
reishi mushroom
resveratrol
silymarin
spirulina
tocotrienols
trans-pterostilbene
tributyrin
trimethylglycine (TMG)
triphala
Urolithin A
vitamin C
vitamin E
seaweed
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
enicostemma littorale
punarnava
picrorhiza kurroa
lingzhi
morus
ferulic acid
ganoderma
polyphenols
anemarrhena asphodeloides
coix
nopal
algae
AMP-activated protein kinase (AMPK)
ashitaba
4-hydroxyisoleucine
7,14-Hydroxy-Docosapentaenoic Acid
Arjuna
Apigenin
Aronia melanocarpa
Antrodia camphorata
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Algal protein
Alisma
Arabinoxylan
Argan nut oil
Anemarrhena
alpha Methyl Tetradecylthioacetic Acid
Apocynin
Arjunolic acid
Borotutu
Brutieridin
Brown Algae
Brassica
Berberis (unspecified)
Baicalein
Blakeslea trispora
Betanin
Bifidobacteria
bile acid
Baicalin
Carqueja
Chebulic acid
Camelina Oil
Coriander
chlorogenic acid
Cynarin
Cruciferous
Chitin-Glucan Complex
Caulerpa okamurae
Copalchi
Curcuma
Corilagin
Crocetin
Cynaropicrin
corosolic acid
Carnosic acid
Diallyl sulfide
Danshen
Dihydromyricetin
DL-Methionine
Decursin
D-Pinitol
Diosgenin
Dithiolthiones
epicatechin
Eriocitrin
Ergothioneine
Erythrodiol
Eicosapentaenoic Acid
Eucommia ulmoides
Fiber
Rhubarb
walnut
Zucchini

Products containing Anthocyanin

We currently have no products on Vitabase that contain this ingredient.