Evidence supporting the use of: Bifidobacterium (mixed)
For the health condition: Fatty Liver Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bifidobacterium (mixed strains) has some scientific evidence supporting its use in the management of Fatty Liver Disease, particularly non-alcoholic fatty liver disease (NAFLD). Several small clinical trials and animal studies have explored the impact of probiotics, including Bifidobacterium species, on liver health. These studies suggest that Bifidobacterium supplementation may help reduce liver fat accumulation, improve liver enzyme levels (such as ALT and AST), and decrease markers of inflammation and oxidative stress. The proposed mechanisms include modulation of the gut microbiota, reduction of gut permeability ("leaky gut"), and subsequent decrease in endotoxin-related inflammation that can contribute to liver damage.

However, while some randomized controlled trials (RCTs) and meta-analyses indicate modest benefit, the overall quality and size of the evidence base are limited. Most studies use mixed probiotic formulations (not Bifidobacterium alone), making it difficult to isolate the effects of Bifidobacterium specifically. Additionally, variations in strains, dosages, and study populations contribute to inconsistent findings.

There is little to no traditional use of Bifidobacterium for fatty liver disease, as probiotics are a relatively recent development in therapeutic interventions. In summary, while there is preliminary scientific validation for Bifidobacterium (mixed) in improving certain outcomes in fatty liver disease, the evidence is moderate at best and further large, high-quality trials are needed to confirm these benefits.

More about Bifidobacterium (mixed)
More about Fatty Liver Disease

Other ingredients used for Fatty Liver Disease

Akkermansia muciniphila
algal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
arjun tree
artichoke
astaxanthin
banaba
barberry
barley
beet
berberine
bifidobacterium bifidum
bifidobacterium longum
black garlic
sesame
branched-chain amino acids
butyrate triglyceride
canola oil
catechins
caterpillar mushroom
cauliflower
chia seed
chicory
chlorella
chokeberry
choline
conjugated linoleic acid (CLA)
turmeric
curcumin
cyclodextrin
dandelion
diallyl disulfide (DADS)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fenugreek
fiber blend (proprietary)
fish oil
fish protein
flavonols
flaxseed
ginger
grape
hesperetin
kelp
l-carnitine
L-glutathione
L-methionine
L-taurine
lecithin
licorice root
liquid liver fractions
marine lipid
medium chain triglycerides (MCT)
milk thistle
naringin
niacin (vitamin B3)
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-9 fatty acids
palmitoleic acid
perilla
phenolic compounds
phosphatidylcholine
phospholipids
prebiotic blend (proprietary)
butyric acid
psyllium
reishi mushroom
resveratrol
silymarin
spirulina
tocotrienols
trans-pterostilbene
tributyrin
trimethylglycine (TMG)
triphala
Urolithin A
vitamin C
vitamin E
seaweed
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
enicostemma littorale
punarnava
picrorhiza kurroa
lingzhi
morus
ferulic acid
ganoderma
polyphenols
anemarrhena asphodeloides
coix
nopal
Algae
AMP-activated protein kinase (AMPK)
ashitaba
4-hydroxyisoleucine
7,14-Hydroxy-Docosapentaenoic Acid
Arjuna
Apigenin
Aronia melanocarpa
Antrodia camphorata
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Algal protein
Alisma
Arabinoxylan
Argan nut oil
Anemarrhena
Alpha methyl Tetradecylthioacetic Acid
Apocynin
Arjunolic acid
Borotutu
Brutieridin
Brown Algae
Brassica
Berberis (unspecified)
Baicalein
Blakeslea trispora
Betanin
Bifidobacteria
bile acid
Baicalin
Carqueja
Chebulic acid
Camelina Oil
Coriander
chlorogenic acid
Cynarin
Cruciferous
Chitin-Glucan Complex
Caulerpa okamurae
Copalchi
Curcuma
Corilagin
Crocetin
Cynaropicrin
corosolic acid
Carnosic acid
Diallyl sulfide
Danshen
Dihydromyricetin
DL-Methionine
Decursin
D-Pinitol
Diosgenin
Dithiolthiones
epicatechin
Eriocitrin
Ergothioneine
Erythrodiol
Eicosapentaenoic Acid
Eucommia ulmoides
Fucoidan
Fiber
Fucosterol
Fatty acids
Flavanones
Fucoxanthin
Flavonolignan
Glutathione
Hydroxycinnamic acid
Hydroxytyrosol
Isosilybin
Jaboticaba
Jurubeba
Job's Tears
Kefir
Lycium
Lactobacillus plantarum
Limonoid
Legume protein
Mangiferin
Myricetin
Monounsaturated Fat
Marine fat
Naringenin
Oleuropein
Oolong Tea
Oligosaccharides
Oxymatrine
Ornithine l-aspartic acid
Oleoylethanolamide
Osthole
Phellodendron
Puerarin
Phlorizin
Phaeophyceae
Pinitol
Phlorotannins
Polydatin
Phthalides
Pu-Er Tea
Purple Tea
Punicalagins
Rebaudioside
Rapeseed Oil
Rhubarb
Schizochytrium Oil
Schizochytrium
Silybin
Syringic acid
Salvianolic acid
Salacia
Schisandrins
Silydianin
Silychristin
S-allylcysteine
Sesamin
Sinensetin
Tetradecylthioacetic acid
Tyrosol
Taxifolin
Thistle
Tangeretin
Tanshinone
trehalose
Taurine
Theabrownin
Ursolic Acid
Varuna
Wax Gourd
Wakame
walnut
Yacon
Yin Chen
Zucchini

Products containing Bifidobacterium (mixed)

We currently have no products on Vitabase that contain this ingredient.