Evidence supporting the use of: Bifidobacterium (various species)
For the health condition: Fatty Liver Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bifidobacterium species have been studied for their potential role in supporting or treating Nonalcoholic Fatty Liver Disease (NAFLD) and related liver conditions. The rationale is based on evidence that gut microbiota play a significant role in liver health via the gut-liver axis. Dysbiosis, or an imbalance in gut microbiota, is frequently observed in patients with fatty liver disease. Probiotic supplementation with Bifidobacterium may help restore microbial balance, reduce systemic inflammation, and improve metabolic parameters.

Several small-scale randomized controlled trials (RCTs) and meta-analyses have evaluated the impact of Bifidobacterium-containing probiotics on fatty liver disease markers. These studies have demonstrated improvements in liver enzymes (such as ALT and AST), reductions in liver fat content (measured by imaging or biomarkers), and improvements in insulin resistance. Mechanistically, Bifidobacterium may exert beneficial effects by strengthening intestinal barrier integrity, reducing endotoxin translocation, and modulating inflammatory pathways.

While these findings are promising, the methodological quality and sample sizes of existing studies vary, and most use multi-strain probiotic formulations rather than Bifidobacterium alone. Therefore, evidence supporting Bifidobacterium for fatty liver disease can be rated as moderate (3/5), indicating scientific validation but with a need for further large, high-quality RCTs to confirm efficacy and optimal dosing.

More about Bifidobacterium (various species)
More about Fatty Liver Disease

Other ingredients used for Fatty Liver Disease

akkermansia muciniphila
algal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
arjun tree
artichoke
astaxanthin
banaba
barberry
barley
beet
berberine
bifidobacterium bifidum
bifidobacterium longum
black garlic
sesame
branched-chain amino acids
butyrate triglyceride
canola oil
catechins
caterpillar mushroom
cauliflower
chia seed
chicory
chlorella
chokeberry
choline
conjugated linoleic acid (CLA)
turmeric
curcumin
cyclodextrin
dandelion
diallyl disulfide (DADS)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fenugreek
fiber blend (proprietary)
fish oil
fish protein
flavonols
flaxseed
ginger
grape
hesperetin
kelp
l-carnitine
l-glutathione
l-methionine
l-taurine
lecithin
licorice root
liquid liver fractions
marine lipid
medium chain triglycerides (MCT)
milk thistle
naringin
niacin (vitamin B3)
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-9 fatty acids
palmitoleic acid
perilla
phenolic acids
phosphatidylcholine
phospholipids
prebiotic blend (proprietary)
butyric acid
psyllium
reishi mushroom
resveratrol
silymarin
spirulina
tocotrienols
trans-pterostilbene
tributyrin
trimethylglycine (TMG)
triphala
Urolithin A
vitamin C
vitamin E
seaweed
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
enicostemma littorale
punarnava
picrorhiza kurroa
lingzhi
morus
ferulic acid
ganoderma
polyphenols
anemarrhena asphodeloides
coix
nopal
algae
AMP-activated protein kinase (AMPK)
ashitaba
4-hydroxyisoleucine
7,14-Hydroxy-Docosapentaenoic Acid
Arjuna
Apigenin
Aronia melanocarpa
Antrodia camphorata
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Algal protein
Alisma
Arabinoxylan
Argan nut oil
Anemarrhena
alpha Methyl Tetradecylthioacetic Acid
Apocynin
Arjunolic acid
Borotutu
Brutieridin
Brown Algae
Brassica
Berberis (unspecified)
Baicalein
Blakeslea trispora
Betanin
Bifidobacteria
bile acid
Baicalin
Carqueja
Chebulic acid
Camelina Oil
Coriander
chlorogenic acid
Cynarin
Cruciferous
Chitin-Glucan Complex
Caulerpa okamurae
Copalchi
Curcuma
Corilagin
Crocetin
Cynaropicrin
corosolic acid
Carnosic acid
Diallyl sulfide
Danshen
Dihydromyricetin
DL-Methionine
Decursin
D-Pinitol
Diosgenin
Dithiolthiones
epicatechin
Eriocitrin
Ergothioneine
Erythrodiol
Eicosapentaenoic Acid
Eucommia ulmoides
Fiber
Rhubarb
walnut
Zucchini

Products containing Bifidobacterium (various species)

We currently have no products on Vitabase that contain this ingredient.