Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Chokeberry (Aronia melanocarpa) is a berry rich in polyphenols and anthocyanins, compounds known for their antioxidant and anti-inflammatory properties. Some scientific evidence suggests that chokeberry supplementation may have beneficial effects in non-alcoholic fatty liver disease (NAFLD). Animal studies and a limited number of small clinical trials have reported that chokeberry extract can reduce markers of oxidative stress, improve lipid profiles, and decrease liver enzyme levels in subjects with fatty liver disease. For example, a randomized controlled trial published in 2017 found that chokeberry juice consumption over two months led to significant reductions in liver enzymes, cholesterol, and oxidative stress markers in NAFLD patients compared to controls. Additionally, preclinical research has shown that chokeberry may decrease hepatic fat accumulation and inflammation in rodent models. However, the overall quality and quantity of human studies are limited, and most research has been conducted on small groups or in experimental animal models rather than large-scale clinical populations. While the mechanisms by which chokeberry could benefit liver health—such as reducing oxidative stress, inflammation, and lipid accumulation—are plausible and supported by some early research, more robust clinical trials are needed to firmly establish efficacy and optimal dosing in humans with fatty liver disease. Thus, while the use of chokeberry for fatty liver disease is supported by initial scientific findings, the evidence base remains preliminary.

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