Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Conjugated linoleic acid (CLA) is a group of polyunsaturated fatty acids found naturally in meat and dairy products. Its use in the context of fatty liver disease (specifically, non-alcoholic fatty liver disease or NAFLD) is primarily based on scientific investigation, mostly in animal models and a limited number of human studies. Research suggests that CLA may improve lipid metabolism, reduce fat accumulation in the liver, and modulate inflammation and oxidative stress, all of which are relevant to fatty liver disease. In rodent models, CLA supplementation has been shown to decrease hepatic steatosis (fat buildup in the liver) and improve biomarkers associated with liver health. These effects are thought to be mediated by CLA's ability to alter gene expression related to lipid metabolism and inflammation. However, evidence from human clinical trials is limited and inconsistent. Some small studies suggest potential benefits of CLA supplementation on liver fat content and metabolic parameters, while others raise concerns about adverse effects, including possible worsening of insulin resistance or liver inflammation with certain isomers of CLA. Overall, the current body of evidence is preliminary, and more robust, large-scale human trials are needed to establish efficacy and safety. Thus, while scientific rationale exists, the strength of evidence supporting CLA for fatty liver disease is modest at best.

More about conjugated linoleic acid (CLA)
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Other ingredients used for Fatty Liver Disease

Other health conditions supported by conjugated linoleic acid (CLA)

Products containing conjugated linoleic acid (CLA)

Designs For Health CLA
Pure Encapsulations CLA 1000 mg
Pure Encapsulations CLA 1000 mg
Douglas Laboratories CLA (Conjugated Linoleic Acid)
Designs For Health Plant Protein Meal
Designs For Health Plant Protein Meal Plus
Designs For Health Plant Protein Meal
Vitabase Super Fat Burner