Evidence supporting the use of: Danshen
For the health condition: Fatty Liver Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Danshen (Salvia miltiorrhiza) is a traditional Chinese herbal medicine that has been used for centuries, primarily for cardiovascular and liver disorders. In recent years, there has been growing scientific interest in its potential for supporting and treating non-alcoholic fatty liver disease (NAFLD). Preclinical studies (in vitro and animal models) indicate that Danshen and its main active compounds, such as tanshinones and salvianolic acids, possess antioxidant, anti-inflammatory, and anti-fibrotic properties. These effects may help ameliorate liver steatosis, reduce oxidative stress, and improve liver function.

Several small-scale clinical studies and meta-analyses from China have reported that Danshen, either alone or in combination with other herbs, can reduce liver enzyme levels, improve liver ultrasound findings, and decrease markers of liver inflammation and fibrosis in patients with NAFLD. However, these studies are often limited by small sample sizes, short durations, and methodological weaknesses such as lack of blinding or placebo controls. Systematic reviews generally conclude that while preliminary evidence is promising, larger, well-designed randomized controlled trials are needed to confirm efficacy and safety.

In summary, there is moderate scientific evidence supporting the use of Danshen for fatty liver disease, mostly from preclinical research and early-phase clinical trials. Use is further supported by its long history in traditional medicine for liver health, but robust clinical validation is still lacking.

More about danshen
More about Fatty Liver Disease

Other ingredients used for Fatty Liver Disease

4-hydroxyisoleucine
7,14-Hydroxy-Docosapentaenoic Acid
Acacetin
Adzuki bean
Akkermansia muciniphila
Algae
algal oil
Algal protein
Alisma
Alpha methyl tetradecylthioacetic acid
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
alpha-lipoic acid
AMP-activated protein kinase (AMPK)
ampelopsin
Anemarrhena
anemarrhena asphodeloides
anthocyanins
Antrodia camphorata
apigenin
apocynin
arabinoxylan
argan nut oil
arjun tree
arjuna
Arjunolic acid
Aronia melanocarpa
artichoke
Ascophyllum nodosum
ashitaba
astaxanthin
astragaloside
avocado
baicalein
baicalin
banaba
barberry
barley
beet
berberine
Berberis (unspecified)
betanin
Bifidobacteria
Bifidobacterium bifidum
Bifidobacterium longum
bile acid
black garlic
Blakeslea trispora
borotutu
branched-chain amino acids
Brassica
Brown Algae
brutieridin
butyrate triglyceride
butyric acid
camelina oil
carnosic acid
carqueja
catechins
caterpillar mushroom
Caulerpa okamurae
cauliflower
chebulic acid
chia seed
chicory
Chitin-Glucan Complex
chlorella
chlorogenic acid
chokeberry
choline
coix
conjugated linoleic acid (CLA)
copalchi
coriander
corilagin
corosolic acid
crocetin
cruciferous
Curcuma
curcumin
cyclodextrin
cynarin
cynaropicrin
D-Pinitol
dandelion
danshen
decursin
diallyl disulfide (DADS)
diallyl sulfide
dihydromyricetin
diosgenin
dithiolthiones
DL-Methionine
eicosapentaenoic acid
Enicostemma littorale
EPA (eicosapentaenoic acid)
epicatechin
epigallocatechin gallate (EGCG)
ergothioneine
eriocitrin
erythrodiol
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fatty acids
fenugreek
ferulic acid
fiber
fiber blend (proprietary)
fish oil
fish protein
flavanones
flavonolignan
flavonols
flaxseed
fucoidan
fucosterol
fucoxanthin
ganoderma
ginger
Glutathione
grape
hesperetin
hydroxycinnamic acid
hydroxytyrosol
isosilybin
Jaboticaba
jiaogulan
Job\'s tears
Jurubeba
Kefir
kelp
l-carnitine
L-glutathione
L-methionine
L-taurine
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lecithin
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licorice root
limonoid
lingzhi
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mangiferin
Marine fat
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medium chain triglycerides (MCT)
Milk thistle
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nicotinamide riboside
nopal
oleanolic acid
oleic acid
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Oleuropein
Oligosaccharides
olive
omega-3 fatty acids
omega-9 fatty acids
oolong tea
ornithine L-aspartic acid
Osthole
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palmitoleic acid
perilla
Phaeophyceae
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phenolic compounds
phlorizin
phlorotannins
phosphatidylcholine
phospholipids
Phthalides
picrorhiza kurroa
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polyphenols
prebiotic blend (proprietary)
psyllium
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punarnava
punicalagins
purple tea
rapeseed oil
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reishi mushroom
resveratrol
rhubarb
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Schisandrins
Schizochytrium
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seaweed
sesame
Sesamin
Silybin
Silychristin
Silydianin
silymarin
Sinensetin
spirulina
Syringic acid
Tangeretin
Tanshinone
Taurine
Taxifolin
Tetradecylthioacetic acid
Theabrownin
Thistle
tocotrienols
Trans-pterostilbene
Trehalose
tributyrin
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turmeric
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vitamin C
vitamin E
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Products containing danshen

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