Synopsis

Source of validity: Scientific
Rating (out of 5): 2

DL-Methionine is an essential amino acid and a precursor for several important biological molecules, including S-adenosylmethionine (SAMe), which plays a key role in hepatic methylation reactions and antioxidant defense. The use of methionine (including its synthetic form, DL-methionine) in the context of fatty liver disease is primarily based on its role in supporting liver function, particularly in the synthesis of glutathione, a crucial antioxidant in the liver.

Animal studies have shown that methionine-deficient diets can induce fatty liver (hepatic steatosis), suggesting that adequate methionine intake is important for normal liver lipid metabolism. In this sense, methionine supplementation is sometimes considered as a supportive measure to maintain healthy liver function and prevent fat accumulation, especially in cases where dietary methionine may be insufficient.

However, direct clinical evidence supporting DL-methionine supplementation as a treatment for established fatty liver disease in humans is limited. Most studies focus on prevention rather than treatment, and some animal studies suggest that excessive methionine intake may have harmful effects, particularly in individuals with compromised liver function. The evidence is stronger in veterinary medicine, where DL-methionine is often used to prevent fatty liver in livestock and poultry.

In summary, while there is a scientific rationale and some experimental evidence for the supportive use of DL-methionine in fatty liver disease, robust clinical trials in humans are lacking, and the overall evidence level is modest.

More about DL-Methionine
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Other ingredients used for Fatty Liver Disease

Akkermansia muciniphila
algal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
arjun tree
artichoke
astaxanthin
banaba
barberry
barley
beet
berberine
bifidobacterium bifidum
bifidobacterium longum
black garlic
sesame
branched-chain amino acids
butyrate triglyceride
canola oil
catechins
caterpillar mushroom
cauliflower
chia seed
chicory
chlorella
chokeberry
choline
conjugated linoleic acid (CLA)
turmeric
curcumin
cyclodextrin
dandelion
diallyl disulfide (DADS)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fenugreek
fiber blend (proprietary)
fish oil
fish protein
flavonols
flaxseed
ginger
grape
hesperetin
kelp
l-carnitine
L-glutathione
L-methionine
L-taurine
lecithin
licorice root
liquid liver fractions
marine lipid
medium chain triglycerides (MCT)
milk thistle
naringin
niacin (vitamin B3)
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-9 fatty acids
palmitoleic acid
perilla
phenolic compounds
phosphatidylcholine
phospholipids
prebiotic blend (proprietary)
butyric acid
psyllium
reishi mushroom
resveratrol
silymarin
spirulina
tocotrienols
trans-pterostilbene
tributyrin
trimethylglycine (TMG)
triphala
Urolithin A
vitamin C
vitamin E
seaweed
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
enicostemma littorale
punarnava
picrorhiza kurroa
lingzhi
morus
ferulic acid
ganoderma
polyphenols
anemarrhena asphodeloides
coix
nopal
Algae
AMP-activated protein kinase (AMPK)
ashitaba
4-hydroxyisoleucine
7,14-Hydroxy-Docosapentaenoic Acid
Arjuna
Apigenin
Aronia melanocarpa
Antrodia camphorata
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Algal protein
Alisma
Arabinoxylan
Argan nut oil
Anemarrhena
Alpha methyl Tetradecylthioacetic Acid
Apocynin
Arjunolic acid
Borotutu
Brutieridin
Brown Algae
Brassica
Berberis (unspecified)
Baicalein
Blakeslea trispora
Betanin
Bifidobacteria
bile acid
Baicalin
Carqueja
Chebulic acid
Camelina Oil
Coriander
chlorogenic acid
Cynarin
Cruciferous
Chitin-Glucan Complex
Caulerpa okamurae
Copalchi
Curcuma
Corilagin
Crocetin
Cynaropicrin
corosolic acid
Carnosic acid
Diallyl sulfide
Danshen
Dihydromyricetin
DL-Methionine
Decursin
D-Pinitol
Diosgenin
Dithiolthiones
epicatechin
Eriocitrin
Ergothioneine
Erythrodiol
Eicosapentaenoic Acid
Eucommia ulmoides
Fucoidan
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Flavanones
Fucoxanthin
Flavonolignan
Glutathione
Hydroxycinnamic acid
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Job's Tears
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Lactobacillus plantarum
Limonoid
Legume protein
Mangiferin
Myricetin
Monounsaturated Fat
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Naringenin
Oleuropein
Oolong Tea
Oligosaccharides
Oxymatrine
Ornithine l-aspartic acid
Oleoylethanolamide
Osthole
Phellodendron
Puerarin
Phlorizin
Phaeophyceae
Pinitol
Phlorotannins
Polydatin
Phthalides
Pu-Er Tea
Purple Tea
Punicalagins
Rebaudioside
Rapeseed Oil
Rhubarb
Schizochytrium Oil
Schizochytrium
Silybin
Syringic acid
Salvianolic acid
Salacia
Schisandrins
Silydianin
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S-allylcysteine
Sesamin
Sinensetin
Tetradecylthioacetic acid
Tyrosol
Taxifolin
Thistle
Tangeretin
Tanshinone
trehalose
Taurine
Theabrownin
Ursolic Acid
Varuna
Wax Gourd
Wakame
walnut
Yacon
Yin Chen
Zucchini

Other health conditions supported by DL-Methionine

Fatty Liver Disease
Hair (loss or thinning)
Liver Detoxification

Products containing DL-Methionine

We currently have no products on Vitabase that contain this ingredient.