Synopsis

Source of validity: Scientific
Rating (out of 5): 2

DL-Methionine is an essential amino acid and a precursor for several important biological molecules, including S-adenosylmethionine (SAMe), which plays a key role in hepatic methylation reactions and antioxidant defense. The use of methionine (including its synthetic form, DL-methionine) in the context of fatty liver disease is primarily based on its role in supporting liver function, particularly in the synthesis of glutathione, a crucial antioxidant in the liver.

Animal studies have shown that methionine-deficient diets can induce fatty liver (hepatic steatosis), suggesting that adequate methionine intake is important for normal liver lipid metabolism. In this sense, methionine supplementation is sometimes considered as a supportive measure to maintain healthy liver function and prevent fat accumulation, especially in cases where dietary methionine may be insufficient.

However, direct clinical evidence supporting DL-methionine supplementation as a treatment for established fatty liver disease in humans is limited. Most studies focus on prevention rather than treatment, and some animal studies suggest that excessive methionine intake may have harmful effects, particularly in individuals with compromised liver function. The evidence is stronger in veterinary medicine, where DL-methionine is often used to prevent fatty liver in livestock and poultry.

In summary, while there is a scientific rationale and some experimental evidence for the supportive use of DL-methionine in fatty liver disease, robust clinical trials in humans are lacking, and the overall evidence level is modest.

More about DL-Methionine
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Acacetin
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Other health conditions supported by DL-Methionine

Fatty Liver Disease
Hair (loss or thinning)
Liver Detoxification

Products containing DL-Methionine

We currently have no products on Vitabase that contain this ingredient.