Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Fish protein has been investigated for its potential benefits in managing Fatty Liver Disease (specifically Non-Alcoholic Fatty Liver Disease, NAFLD). Scientific studies, mostly in animal models and some small human trials, suggest that dietary fish protein may exert beneficial effects on liver health. This is attributed to several mechanisms: fish protein is typically lower in saturated fat and higher in certain amino acids compared to red meat; it also may help modulate lipid metabolism and reduce liver fat accumulation. Additionally, fish proteins often come with associated nutrients, such as omega-3 fatty acids, which are well-documented for their anti-inflammatory and lipid-lowering effects, although in most studies, the distinction between the effects of fish protein itself and those of omega-3s can be difficult to clarify.

A number of animal studies have shown that diets rich in fish protein can improve liver enzyme profiles, decrease hepatic fat deposition, and reduce markers of inflammation in models of fatty liver. Human clinical evidence is more limited, but a few small trials have suggested improvements in liver function tests and liver fat content when fish or fish protein is incorporated into the diet of individuals with NAFLD. These positive findings are believed to be partially due to improved lipid metabolism and insulin sensitivity. However, more large-scale, well-controlled human studies are needed to confirm these effects and determine optimal intake.

Overall, while the evidence is promising and provides a scientific rationale, it is not yet conclusive, warranting a moderate evidence rating of 3 out of 5.

More about fish protein
More about Fatty Liver Disease

Other ingredients used for Fatty Liver Disease

Other health conditions supported by fish protein

Products containing fish protein

Metagenics Vasotensin®