Evidence supporting the use of: Fucoidan
For the health condition: Fatty Liver Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Fucoidan is a sulfated polysaccharide mainly extracted from brown seaweeds. In recent years, it has attracted attention for its potential health benefits, including effects on liver health and fatty liver disease (non-alcoholic fatty liver disease, NAFLD). Several preclinical studies (in vitro and animal models) have suggested that fucoidan may exert hepatoprotective effects by reducing oxidative stress, inflammation, and lipid accumulation in liver tissues. For example, research published in Marine Drugs (2019) and International Journal of Molecular Sciences (2022) reported that fucoidan supplementation improved markers of liver function and decreased fat deposits in the liver of animal models fed high-fat diets. Proposed mechanisms include modulation of AMPK and PPAR pathways, leading to altered lipid metabolism and reduced inflammation.

However, clinical studies in humans are very limited. There are only a few small-scale trials or observational studies, and these do not provide strong evidence regarding efficacy or safety for treating or managing fatty liver disease. As such, while there is scientific rationale and some encouraging preclinical data, the evidence does not yet rise to a high level of validation. More well-designed, large-scale human trials are needed before fucoidan can be confidently recommended for fatty liver disease.

More about fucoidan
More about Fatty Liver Disease

Other ingredients used for Fatty Liver Disease

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Acacetin
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Akkermansia muciniphila
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algal oil
Algal protein
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alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
alpha-lipoic acid
AMP-activated protein kinase (AMPK)
ampelopsin
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anemarrhena asphodeloides
anthocyanins
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apigenin
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arabinoxylan
argan nut oil
arjun tree
arjuna
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Aronia melanocarpa
artichoke
Ascophyllum nodosum
ashitaba
astaxanthin
astragaloside
avocado
baicalein
baicalin
banaba
barberry
barley
beet
berberine
Berberis (unspecified)
betanin
Bifidobacteria
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bile acid
black garlic
Blakeslea trispora
borotutu
branched-chain amino acids
Brassica
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brutieridin
butyrate triglyceride
butyric acid
camelina oil
carnosic acid
carqueja
catechins
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Caulerpa okamurae
cauliflower
chebulic acid
chia seed
chicory
Chitin-Glucan Complex
chlorella
chlorogenic acid
chokeberry
choline
coix
conjugated linoleic acid (CLA)
copalchi
coriander
corilagin
corosolic acid
crocetin
cruciferous
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cyclodextrin
cynarin
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dandelion
danshen
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diallyl disulfide (DADS)
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dihydromyricetin
diosgenin
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eicosapentaenoic acid
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epicatechin
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ergothioneine
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fenugreek
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fiber
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flavanones
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l-carnitine
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Products containing fucoidan

We currently have no products on Vitabase that contain this ingredient.