Evidence supporting the use of: Fucoxanthin
For the health condition: Fatty Liver Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Fucoxanthin is a carotenoid primarily found in brown seaweed, and recent research has investigated its potential for supporting metabolic health, including fatty liver disease (non-alcoholic fatty liver disease, NAFLD). Preclinical studies in animals have shown that fucoxanthin supplementation can reduce liver fat accumulation, improve lipid metabolism, and decrease markers of inflammation and oxidative stress in the liver. These effects are believed to be mediated through mechanisms such as upregulation of thermogenic protein UCP1, modulation of lipid metabolism genes, and anti-inflammatory pathways.
However, human data are limited. A few small-scale clinical trials suggest that fucoxanthin-containing supplements may help reduce body and liver fat in obese individuals, but these studies often combine fucoxanthin with other ingredients, making it difficult to isolate its effects. The evidence remains preliminary, and there is not yet robust, large-scale, placebo-controlled clinical trial data confirming its efficacy or safety for treating fatty liver disease specifically. Therefore, while there is a growing scientific rationale based on animal and early human studies, the overall quality and quantity of evidence supporting the use of fucoxanthin for fatty liver disease are still considered low to moderate.
In conclusion, the use of fucoxanthin for fatty liver disease is supported by some scientific studies, mainly in animals, with limited preliminary human evidence. More research is needed before it can be recommended with confidence for this condition.
Other ingredients used for Fatty Liver Disease
4-hydroxyisoleucine7,14-Hydroxy-Docosapentaenoic Acid
Acacetin
Adzuki bean
Akkermansia muciniphila
Algae
algal oil
Algal protein
Alisma
Alpha methyl tetradecylthioacetic acid
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
alpha-lipoic acid
AMP-activated protein kinase (AMPK)
ampelopsin
Anemarrhena
anemarrhena asphodeloides
anthocyanins
Antrodia camphorata
apigenin
apocynin
arabinoxylan
argan nut oil
arjun tree
arjuna
Arjunolic acid
Aronia melanocarpa
artichoke
Ascophyllum nodosum
ashitaba
astaxanthin
astragaloside
avocado
baicalein
baicalin
banaba
barberry
barley
beet
berberine
Berberis (unspecified)
betanin
Bifidobacteria
Bifidobacterium bifidum
Bifidobacterium longum
bile acid
black garlic
Blakeslea trispora
borotutu
branched-chain amino acids
Brassica
Brown Algae
brutieridin
butyrate triglyceride
butyric acid
camelina oil
carnosic acid
carqueja
catechins
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Caulerpa okamurae
cauliflower
chebulic acid
chia seed
chicory
Chitin-Glucan Complex
chlorella
chlorogenic acid
chokeberry
choline
coix
conjugated linoleic acid (CLA)
copalchi
coriander
corilagin
corosolic acid
crocetin
cruciferous
Curcuma
curcumin
cyclodextrin
cynarin
cynaropicrin
D-Pinitol
dandelion
danshen
decursin
diallyl disulfide (DADS)
diallyl sulfide
dihydromyricetin
diosgenin
dithiolthiones
DL-Methionine
eicosapentaenoic acid
Enicostemma littorale
EPA (eicosapentaenoic acid)
epicatechin
epigallocatechin gallate (EGCG)
ergothioneine
eriocitrin
erythrodiol
Eucommia ulmoides
fatty acids
fenugreek
ferulic acid
fiber
fiber blend (proprietary)
fish oil
fish protein
flavanones
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flaxseed
fucoidan
fucosterol
fucoxanthin
ganoderma
ginger
Glutathione
grape
hesperetin
hydroxycinnamic acid
hydroxytyrosol
isosilybin
Jaboticaba
jiaogulan
Job\'s tears
Jurubeba
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kelp
l-carnitine
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L-methionine
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Lactobacillus plantarum
lecithin
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licorice root
limonoid
lingzhi
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Lycium
mangiferin
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medium chain triglycerides (MCT)
Milk thistle
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Morus
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Myricetin
Naringenin
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nicotinamide riboside
nopal
oleanolic acid
oleic acid
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olive
omega-3 fatty acids
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oolong tea
ornithine L-aspartic acid
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palmitoleic acid
perilla
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phosphatidylcholine
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psyllium
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punarnava
punicalagins
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rapeseed oil
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resveratrol
rhubarb
S-allylcysteine
Salacia
Salvianolic acid
Schisandrins
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seaweed
sesame
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silymarin
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spirulina
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Taurine
Taxifolin
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Theabrownin
Thistle
tocotrienols
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turmeric
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Varuna
vitamin C
vitamin E
Wakame
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Yin Chen
Zinc
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β-nicotinamide mononucleotide (NMN)