Evidence supporting the use of: Kelp
For the health condition: Fatty Liver Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Kelp, a type of brown seaweed, has gained attention in recent years as a potential supplement for supporting liver health, including in the context of Fatty Liver Disease (Non-Alcoholic Fatty Liver Disease, NAFLD). There is some preliminary scientific evidence suggesting that compounds found in kelp, such as fucoxanthin, alginates, and polyphenols, may exert beneficial effects on lipid metabolism, inflammation, and oxidative stress — all of which are relevant factors in NAFLD. Animal studies have shown that fucoxanthin can help reduce hepatic fat accumulation and improve markers of liver function. For example, a 2012 study in mice found that dietary fucoxanthin reduced body weight gain and liver fat content. Other research has demonstrated antioxidant and anti-inflammatory properties of kelp extracts, which could theoretically provide liver-protective effects.

However, human clinical trials are very limited, and the available studies are often small or use mixed seaweed extracts, making it difficult to isolate the effects of kelp itself. Systematic reviews generally conclude that while there is promise, the evidence base remains insufficient for strong recommendations regarding kelp supplementation for fatty liver disease. Thus, kelp's use in this context is justified by emerging but not robust scientific evidence, and it should not replace conventional management. People with thyroid disorders or those taking certain medications should be cautious, as kelp is high in iodine and may interact with thyroid function.

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4-hydroxyisoleucine
7,14-Hydroxy-Docosapentaenoic Acid
Acacetin
Adzuki bean
Akkermansia muciniphila
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algal oil
Algal protein
Alisma
Alpha methyl tetradecylthioacetic acid
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
alpha-lipoic acid
AMP-activated protein kinase (AMPK)
ampelopsin
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anemarrhena asphodeloides
anthocyanins
Antrodia camphorata
apigenin
apocynin
arabinoxylan
argan nut oil
arjun tree
arjuna
Arjunolic acid
Aronia melanocarpa
artichoke
Ascophyllum nodosum
ashitaba
astaxanthin
astragaloside
avocado
baicalein
baicalin
banaba
barberry
barley
beet
berberine
Berberis (unspecified)
betanin
Bifidobacteria
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bile acid
black garlic
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borotutu
branched-chain amino acids
Brassica
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brutieridin
butyrate triglyceride
butyric acid
camelina oil
carnosic acid
carqueja
catechins
caterpillar mushroom
Caulerpa okamurae
cauliflower
chebulic acid
chia seed
chicory
Chitin-Glucan Complex
chlorella
chlorogenic acid
chokeberry
choline
coix
conjugated linoleic acid (CLA)
copalchi
coriander
corilagin
corosolic acid
crocetin
cruciferous
Curcuma
curcumin
cyclodextrin
cynarin
cynaropicrin
D-Pinitol
dandelion
danshen
decursin
diallyl disulfide (DADS)
diallyl sulfide
dihydromyricetin
diosgenin
dithiolthiones
DL-Methionine
eicosapentaenoic acid
Enicostemma littorale
EPA (eicosapentaenoic acid)
epicatechin
epigallocatechin gallate (EGCG)
ergothioneine
eriocitrin
erythrodiol
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fatty acids
fenugreek
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fiber
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fish protein
flavanones
flavonolignan
flavonols
flaxseed
fucoidan
fucosterol
fucoxanthin
ganoderma
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Glutathione
grape
hesperetin
hydroxycinnamic acid
hydroxytyrosol
isosilybin
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jiaogulan
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kelp
l-carnitine
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L-methionine
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lecithin
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mangiferin
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ornithine L-aspartic acid
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palmitoleic acid
perilla
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phlorizin
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phosphatidylcholine
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picrorhiza kurroa
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polyphenols
prebiotic blend (proprietary)
psyllium
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punarnava
punicalagins
purple tea
rapeseed oil
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resveratrol
rhubarb
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sesame
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silymarin
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spirulina
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Tetradecylthioacetic acid
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tocotrienols
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tributyrin
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vitamin E
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