Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-taurine has been investigated for its potential benefits in the management of Fatty Liver Disease (FLD), including both alcoholic and non-alcoholic forms. Preclinical studies—primarily in animal models—suggest that taurine may help reduce hepatic steatosis (fat accumulation in the liver), inflammation, and oxidative stress. These effects are believed to be due to taurine's antioxidant properties, its ability to modulate lipid metabolism, and its role in stabilizing cell membranes.

Some small human studies and clinical trials have been conducted. For example, a few pilot studies suggest taurine supplementation (typically at doses of 1.5–3 grams per day) can improve certain biomarkers of liver function and decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD). However, these studies are limited in size, duration, and methodological quality. Larger, high-quality randomized controlled trials are lacking.

Overall, while early evidence is promising and there is a plausible biological rationale for taurine’s use in FLD, the evidence is not yet robust enough to recommend taurine as a standard therapy. Current support is based primarily on animal studies and small clinical trials, so the evidence level is rated as 2 out of 5. Taurine should not replace established treatments for FLD, such as lifestyle modification and management of metabolic risk factors, but may be considered as a complementary approach pending further research.

More about L-taurine
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