Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Olive and olive-derived products, particularly extra virgin olive oil, have growing scientific evidence supporting their beneficial effects in the management of fatty liver disease, especially non-alcoholic fatty liver disease (NAFLD). Several animal studies and human clinical trials suggest that olive oil's high content of monounsaturated fatty acids (MUFAs), mainly oleic acid, and its polyphenols (such as hydroxytyrosol and oleuropein), exert anti-inflammatory, antioxidant, and lipid-lowering effects. These properties may decrease hepatic fat accumulation, improve insulin sensitivity, and reduce markers of liver inflammation and oxidative stress.

In human studies, adherence to a Mediterranean diet (rich in olive oil) has been associated with improvements in liver fat content and serum transaminase levels in NAFLD patients. While not all studies use olive oil in isolation, it is a central fat source in the Mediterranean diet, and its specific supplementation has been shown to favorably affect liver enzymes and fat accumulation in some randomized controlled trials.

However, while the evidence is promising, it is not yet conclusive enough for olive oil to be considered a standalone treatment for fatty liver disease. Further large-scale, long-term clinical trials are needed to establish definitive recommendations. Nonetheless, replacing saturated fats with olive oil in the diet is generally considered beneficial for overall metabolic and liver health.

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