Evidence supporting the use of: Phellodendron
For the health condition: Fatty Liver Disease

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Phellodendron, particularly the bark of Phellodendron amurense (commonly known as Amur cork tree), has a long history of use in Traditional Chinese Medicine (TCM). In TCM, Phellodendron is considered a "heat-clearing" and "dampness-drying" herb, commonly prescribed for liver-related issues, including symptoms thought to relate to what modern medicine describes as fatty liver disease. While the traditional context for its use is based on patterns of disharmony (such as damp-heat in the liver and gallbladder), it is important to note that this does not directly correspond to the biomedical understanding of non-alcoholic fatty liver disease (NAFLD).

There is limited scientific evidence supporting the efficacy of Phellodendron in the treatment or management of fatty liver disease. Some preclinical studies in animals suggest that extracts of Phellodendron (or its active constituent, berberine) may have hepatoprotective and lipid-lowering effects, which could theoretically benefit fatty liver conditions. However, robust clinical trials in humans are lacking. The evidence to date is insufficient to establish efficacy or safety for this purpose according to modern medical standards. Thus, while its use is justified by traditional practice, scientific validation remains limited.

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Products containing Phellodendron

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