Evidence supporting the use of: Unsaturated fatty acid
For the health condition: Fatty Liver Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Unsaturated fatty acids, particularly polyunsaturated fatty acids (PUFAs) like omega-3 fatty acids (e.g., EPA and DHA), have been studied for their role in the management of non-alcoholic fatty liver disease (NAFLD). Several clinical trials and meta-analyses suggest that supplementation with omega-3 PUFAs can reduce liver fat content and improve liver enzyme levels in patients with NAFLD. The proposed mechanisms include improving lipid metabolism, reducing hepatic triglyceride accumulation, and exerting anti-inflammatory effects within the liver. For example, a meta-analysis published in Alimentary Pharmacology & Therapeutics (2016) found that omega-3 supplementation was associated with significant improvements in liver fat, although effects on liver histology were less consistent. The American Association for the Study of Liver Diseases (AASLD) guidelines also mention omega-3 fatty acids as a potential adjunct for reducing liver fat in NAFLD, though they caution that evidence is not definitive for all clinical outcomes. Monounsaturated fatty acids (like those found in olive oil) may also be beneficial as part of a Mediterranean-style diet, which is often recommended for NAFLD. However, despite promising results, the overall evidence is rated moderate: while there is scientific validation for the use of unsaturated fatty acids to support fatty liver health, results are sometimes inconsistent, and more large-scale, long-term trials are needed to confirm efficacy and determine optimal dosing.
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Other ingredients used for Fatty Liver Disease
akkermansia muciniphilaalgal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
arjun tree
artichoke
astaxanthin
banaba
barberry
barley
beet
berberine
bifidobacterium bifidum
bifidobacterium longum
black garlic
sesame
branched-chain amino acids
butyrate triglyceride
canola oil
catechins
caterpillar mushroom
cauliflower
chia seed
chicory
chlorella
chokeberry
choline
conjugated linoleic acid (CLA)
turmeric
curcumin
cyclodextrin
dandelion
diallyl disulfide (DADS)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fenugreek
fiber blend (proprietary)
fish oil
fish protein
flavonols
flaxseed
ginger
grape
hesperetin
kelp
l-carnitine
l-glutathione
l-methionine
l-taurine
lecithin
licorice root
liquid liver fractions
marine lipid
medium chain triglycerides (MCT)
milk thistle
naringin
niacin (vitamin B3)
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-9 fatty acids
palmitoleic acid
perilla
phenolic acids
phosphatidylcholine
phospholipids
prebiotic blend (proprietary)
butyric acid
psyllium
reishi mushroom
resveratrol
silymarin
spirulina
tocotrienols
trans-pterostilbene
tributyrin
trimethylglycine (TMG)
triphala
Urolithin A
vitamin C
vitamin E
seaweed
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
enicostemma littorale
punarnava
picrorhiza kurroa
lingzhi
morus
ferulic acid
ganoderma
polyphenols
anemarrhena asphodeloides
coix
nopal
algae
AMP-activated protein kinase (AMPK)
ashitaba
4-hydroxyisoleucine
7,14-Hydroxy-Docosapentaenoic Acid
Arjuna
Apigenin
Aronia melanocarpa
Antrodia camphorata
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Algal protein
Alisma
Arabinoxylan
Argan nut oil
Anemarrhena
alpha Methyl Tetradecylthioacetic Acid
Apocynin
Arjunolic acid
Borotutu
Brutieridin
Brown Algae
Brassica
Berberis (unspecified)
Baicalein
Blakeslea trispora
Betanin
Bifidobacteria
bile acid
Baicalin
Carqueja
Chebulic acid
Camelina Oil
Coriander
chlorogenic acid
Cynarin
Cruciferous
Chitin-Glucan Complex
Caulerpa okamurae
Copalchi
Curcuma
Corilagin
Crocetin
Cynaropicrin
corosolic acid
Carnosic acid
Diallyl sulfide
Danshen
Dihydromyricetin
DL-Methionine
Decursin
D-Pinitol
Diosgenin
Dithiolthiones
epicatechin
Eriocitrin
Ergothioneine
Erythrodiol
Eicosapentaenoic Acid
Eucommia ulmoides
Fiber
Rhubarb
walnut
Zucchini
Other health conditions supported by Unsaturated fatty acid
Alzheimer's DiseaseAngina
Arteriosclerosis
Arthritis
Asthma
Blood Clots (prevention of)
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Congestive Heart Failure
Depression
Diabetes
Fatty Liver Disease
Free Radical Damage
Heart (weakness)
Heart Fibrillation or Palpitations
Hypertension
Inflammation
Inflammatory Bowel Disorders
Memory and Brain Function
Metabolic Syndrome
Migraine
Multiple Sclerosis
Osteoporosis
Parkinson's Disease
Peripheral Neuropathy
Psoriasis
Rheumatoid Arthritis
Stress
Strokes
Triglycerides (high)
Wounds and Sores